DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6w1 and BAS1

DIOPT Version :9

Sequence 1:	NP_001286145.1	Gene:	Cyp6w1 / 35543	FlyBaseID:	FBgn0033065	Length:	514	Species:	Drosophila melanogaster
Sequence 2:	NP_180239.1	Gene:	BAS1 / 817212	AraportID:	AT2G26710	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	529	Identity:	135/529 - (25%)
Similarity:	225/529 - (42%)	Gaps:	91/529 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLLLLLGSLTIV----FYIWQRRTLSFWERHGVKY-IRPFP----------VVGCTREFLTAKV 50
            :|:|.::.||.||    ...|:.|.:   |.|..|. ||..|          :||...:..:..:
plant    13 VLVLSVILSLVIVKGMSLLWWRPRKI---EEHFSKQGIRGPPYHFFIGNVKELVGMMLKASSHPM 74

  Fly    51 PFFEQI-----QKFHEAPGFENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQTDPH 110
            ||...|     ..:|.........|: |:......|.:.|.:||:.:..|...|..|   :..|.
plant    75 PFSHNILPRVLSFYHHWRKIYGATFL-VWFGPTFRLTVADPDLIREIFSKSEFYEKN---EAHPL 135

  Fly   111 NDALGYKNLFFARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDS-AERLGSGTEVQVKD 174
            ...|....|...:...|...|..|||.|....:|.:.|:::|...::.|. :::|....||:| |
plant   136 VKQLEGDGLLSLKGEKWAHHRKIISPTFHMENLKLLVPVVLKSVTDMVDKWSDKLSENGEVEV-D 199

  Fly   175 LCSRF---TTDLIATIAFGVEANALQDAKSEFFYHNRAIFSLTLSRGIDFAIIF---MIPALASL 233
            :...|   |.|:|:..|||   ::.:|        .||:|.|...:.:..|..|   .||.....
plant   200 VYEWFQILTEDVISRTAFG---SSYED--------GRAVFRLQAQQMLLCAEAFQKVFIPGYRFF 253

  Fly   234 -ARVKLFSRETTKFIRSSVNYVLKERERT-----GEK-----RNDLIDILLALKREAAANPGKMS 287
             .|..|.|.:..|.||.|:..:::.|.:.     ||:     ..||:.:::            .:
plant   254 PTRGNLKSWKLDKEIRKSLLKLIERRRQNAIDGEGEECKEPAAKDLLGLMI------------QA 306

  Fly   288 KEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQE 352
            |.|.:..:|.:...|..||.:|:::.:|.|...|:.:...|.:.|.|::...|..|..:.:.:.:
plant   307 KNVTVQDIVEECKSFFFAGKQTTSNLLTWTTILLSMHPEWQAKARDEVLRVCGSRDVPTKDHVVK 371

  Fly   353 MPYLSQVVNETLRKY-PIVGYIERECSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYW 416
            :..||.::||:||.| |||..|.|..|....|         ..::|.|..:.:..:|||.|...|
plant   372 LKTLSMILNESLRLYPPIVATIRRAKSDVKLG---------GYKIPCGTELLIPIIAVHHDQAIW 427

  Fly   417 -PDPEKYDPERF-NSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKT 479
             .|..:::|.|| :...|...:...::|||:|.|.|||..|.:||:||.|..:::...||.
plant   428 GNDVNEFNPARFADGVPRAAKHPVGFIPFGLGVRTCIGQNLAILQAKLTLAVMIQRFTFHL---- 488

  Fly   480 IKKIEWAPT 488
                  |||
plant   489 ------APT 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_001286145.1	p450	34..501	CDD:278495	123/491 (25%)
BAS1	NP_180239.1	CYP734	85..509	CDD:410732	116/454 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810