Protein Alignment Cyp6w1 and cyp3a4.2

DIOPT Version :9

• Sequence 1: NP_001286145.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001015786.1
• Gene: cyp3a4.2 / 548503
• XenbaseID: XB-GENE-971750
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 514
• Identity: 143/514 - (27%)
• Similarity: 253/514 - (49%)
• Gaps: 45/514 - (8%)

  Fly     2 LLLLLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPF-FEQIQKFHEAPGF 65
            :||..|..|.:::.||   ...::::.|:....|.|.:|...||....|.| .|..:|:.:
 Frog    13 ILLAALLVLILLYGIW---PYGYFKKMGIPGPTPLPFIGTFLEFRKGMVQFDTECFKKYGK---- 70

  Fly    66 ENEPFVGVYMTHRPALVIRDLELIKTVMIKK-FQYFNNRVLQTDPHNDALG---YKNLFFARSPG 126
                ..|.|...:|.|.|.|..:|||:::|: :..|.||      .|..|.   ...:..|....
 Frog    71 ----MWGTYDGRQPVLAIMDPAIIKTILVKECYTNFTNR------RNFGLNGPFESAITIAEDEQ 125

  Fly   127 WRELRTKISPVFTSGKIKQMYPLMVK----IGKNLQDSAERLGSGTEVQVKDLCSRFTTDLIATI 187
            |:.:|..:||.|||||:|:|:.:|..    :.||:|...|:   ......||:...::.|:|.:.
 Frog   126 WKRIRNVLSPTFTSGKLKEMFQIMKDYSDILVKNIQGYVEK---DEPCATKDVIGAYSMDVITST 187

  Fly   188 AFGVEANALQDAKSEFFYHNRAIFSLTLSRGIDFAII---FMIPALASLARVKLFSRETTKFIRS 249
            :|.|..::|......|..|.:.:....|...:...::   |:.|.|..| .:....::.|:|..:
 Frog   188 SFSVNIDSLNKPSDPFVIHMKKLLKTGLLSPLLILVVIFPFLRPILEGL-NLNFVPKDFTEFFMN 251

  Fly   250 SVNYVLKERERTGEK--RNDLIDILLALKREAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSAS 312
            :|. ..:|:.:.|:.  |.||:.:::..:.....:.....|.:....::||:.:|..||:||:::
 Frog   252 AVT-SFREKRKKGDHSGRVDLLQLMMDSRTTGGNDLSNKHKALTDAEIMAQSVIFIVAGYETTST 315

  Fly   313 TMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYIEREC 377
            .::...|.||.:..:|.||.:||..|..|:...:|:.:.:|.||..|:.||||.:|..|.:||..
 Frog   316 ALSYLFYNLATHPDVQQRLHEEIDSFLPDKASPTYDILMQMEYLDMVIQETLRLFPPAGRLERVS 380

  Fly   378 SQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYMP 442
            .|..|        .:.:.:|.|:...:....:.|||:|||:||::.||||:..||.......::|
 Frog   381 KQNVE--------INGVSIPKGIVTLIPAYVLQRDPEYWPEPEEFRPERFSKENRATHTPFTFLP 437

  Fly   443 FGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIEWAPTSPVMASKRDIILR 501
            ||.|||||||:|..||..|:.:|.:|:|.....|.:|:..:|:: |...:..|:.|:|:
 Frog   438 FGDGPRNCIGLRFALLSMKVAIVTLLQNFSVRPCAETLIPMEFS-TIGFLQPKKPIVLK 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_001286145.1	p450	34..501	CDD:278495	135/480 (28%)
cyp3a4.2	NP_001015786.1	p450	39..496	CDD:365848	136/485 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	239	1.000	Domainoid score	I2234
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3174
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm9369
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060