Protein Alignment Cyp6w1 and Cyp26c1

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001098671.1
• Gene: Cyp26c1 / 546726
• MGIID: 2679699
• Length: 518
• Species: Mus musculus
• Alignment Length: 543
• Identity: 128/543 - (23%)
• Similarity: 205/543 - (37%)
• Gaps: 133/543 - (24%)

  Fly     5 LLLGSLTIVFYIWQRR-TLS-FWERHGVKYIRPFPVVGCTREFLTAKVPFFEQIQKFHEAPGFEN 67
            ||||   :...:|..| ||| .|..     ..|.|.......|....:.:..|..:||.:   ..
Mouse    24 LLLG---LAQQLWTLRWTLSRDWAS-----TLPLPKGSMGWPFFGETLHWLVQGSRFHSS---RR 77

  Fly    68 EPFVGVYMTH---RPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDA---LGYKNLFFARSPG 126
            |.:..|:.||   ||.:.:...|.::|:::.:     :|::::.....|   ||...|..|....
Mouse    78 ERYGTVFKTHLLGRPVIRVSGAENVRTILLGE-----HRLVRSQWPQSAHILLGSHTLLGAVGEP 137

  Fly   127 WRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSAER-----LGSGTEVQVKDLCSRFTTDLIAT 186
            .|:.|..::.||:...::|..|       .||.:..|     ..:...|.|.......|..:.|.
Mouse   138 HRQRRKVLARVFSRSSLEQFVP-------RLQGALRREVRSWCAAQRPVAVYQAAKALTFRMAAR 195

  Fly   187 IAFGVEANALQDAKSEFFYHN-----RAIFSLTLS-------RGIDFAIIFMIPALASLARVKLF 239
            |..|::   |.:|:.....|.     ..:|||.|.       :||             .||.:|:
Mouse   196 ILLGLQ---LDEARCTELAHTFEQLVENLFSLPLDVPFSGLRKGI-------------RARDQLY 244

  Fly   240 SRETTKFIRSSVNYVLKERERTGEKRNDLIDILLALKREAAANPGKMS-KEVDLDYLVAQAAVFQ 303
                 :.:..:|...|:|:: |.|. .|.:.:::...||....|.... ||:.::.|.
Mouse   245 -----EHLDEAVAEKLQEKQ-TAEP-GDALLLIINSARELGHEPSVQELKELAVELLF------- 295

  Fly   304 TAGFETSASTMTMTLYELAKNEALQDRLRQEI------------------VDFFGDEDHISYERI 350
             |.|.|:||..|..:..|.::.|...:::||:                  ....|.|..:|...:
Mouse   296 -AAFFTTASASTSLILLLLQHPAAITKIQQELSAQGLGRACTCTPRASGSPPDCGCEPDLSLAML 359

  Fly   351 QEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPFH--NMELPHGMSIYMS------TV 407
            ..:.|:..||.|.||..|.|          :.|.|..|..|.  ..::|.|.|:..|      |.
Mouse   360 GRLRYVDCVVKEVLRLLPPV----------SGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETA 414

  Fly   408 AVHRDPQYWPDPEKYDPERFNSSNRDNLNMDA---YMPFGVGPRNCIGMRLGLLQSKLGLVHILR 469
            ||:|.|     ||.:|||||...:.|......   |:|||.|.|:|:|..|.....:|..|.::|
Mouse   415 AVYRSP-----PEGFDPERFGVESGDARGSGGRFHYIPFGGGARSCLGQELAQAVLQLLAVELVR 474

  Fly   470 NHRFHTCDKTIKKIEWAPTSPVM 492
            ..|:...         .|..|||
Mouse   475 TARWELA---------TPAFPVM 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	112/479 (23%)
Cyp26c1	NP_001098671.1	cytochrome_P450	59..504	CDD:477761	115/500 (23%)