Protein Alignment Cyp6w1 and Cyp3a41a

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_059092.2
• Gene: Cyp3a41a / 53973
• MGIID: 1858451
• Length: 504
• Species: Mus musculus
• Alignment Length: 525
• Identity: 154/525 - (29%)
• Similarity: 276/525 - (52%)
• Gaps: 65/525 - (12%)

  Fly     5 LLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPFFEQIQKF----HEAPGF 65
            :||..:.::.|.:..||...:::.|:...:|.|       ||...:.:::.:.||    :|..|
Mouse    13 VLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLP-------FLGTVLNYYKGLWKFDMECYEKYG- 69

  Fly    66 ENEPFVGVYMTHRPALVIRDLELIKTVMIKK-FQYFNNRVLQTDPHNDALGY--KNLFFARSPGW 127
               ...|::....|..||.|.|:||.|::|: |..|.|| .:..|    :|.  |.:..::...|
Mouse    70 ---KTWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNR-REFGP----VGIMSKAISISKDEEW 126

  Fly   128 RELRTKISPVFTSGKIKQMYPLMVKIG----KNLQDSAERLGSGTEVQVKDLCSRFTTDLIATIA 188
            :..|..:||.|||||:|:|:|::.:.|    |.|...||:   |..|.:||:...::.|:|.:.:
Mouse   127 KRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEK---GKPVTMKDVLGAYSIDVITSTS 188

  Fly   189 FGVEANALQDAKSEFFYHNRAIFSLTLSRGIDFAII---FMIPALASLARVKLFSRETTKFIRSS 250
            |||..::|.:.:..|....:.|..:.....:.|:::   |:.|....| .:.:|.:::.:|.:..
Mouse   189 FGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYEML-NICMFPKDSIEFFKKF 252

  Fly   251 VNYVLKERERTGEK-RNDLIDILLALKREAAANPGKMSKEVDLD------YLVAQAAVFQTAGFE 308
            ||.:.:.|..:.:| |.|.:.:::        |....||:.|..      .:.||:.||..||:|
Mouse   253 VNRMKESRLDSKQKHRVDFLQLMM--------NAHNNSKDKDSHKALSDMEITAQSIVFIFAGYE 309

  Fly   309 TSASTMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYI 373
            |::||::.|||.||.:..:|.:|::||.:...::...:|:.:.||.||..|:|||||.|||...:
Mouse   310 TTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRL 374

  Fly   374 ERECSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMD 438
            ||.|.:..|        .:.:.:|.|.::.:.:.|:|.|||:||:||::.||||:..|:.:::..
Mouse   375 ERFCKKDVE--------LNGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPY 431

  Fly   439 AYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIEWA------PTSPVMAS--K 495
            .|||||:|||||||||...:..||.|..:::|..|..|.:|...::.:      |..|::..  .
Mouse   432 LYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGLLQPEKPIVLKVVP 496

  Fly   496 RDIIL 500
            ||:::
Mouse   497 RDVVI 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	139/455 (31%)
Cyp3a41a	NP_059092.2	CYP3A	67..493	CDD:410743	139/454 (31%)