Protein Alignment Cyp6w1 and Cyp4a1

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_787031.1
• Gene: Cyp4a1 / 50549
• RGDID: 68945
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 142/563 - (25%)
• Similarity: 231/563 - (41%)
• Gaps: 140/563 - (24%)

  Fly     2 LLLLLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPF-----FEQIQKFHE 61
            |||||:.:  :.||: ||:.|       :|..:.||           ..||     .:|.|...|
  Rat    27 LLLLLVKA--VQFYL-QRQWL-------LKAFQQFP-----------SPPFHWFFGHKQFQGDKE 70

  Fly    62 APGF----ENEP--FVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDA------- 113
            ....    ||.|  |...:...:..|::.|.:.:|.::.:           :||..:.
  Rat    71 LQQIMTCVENFPSAFPRWFWGSKAYLIVYDPDYMKVILGR-----------SDPKANGVYRLLAP 124

  Fly   114 -LGYKNLFFARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSA-------ERL-GSGTE 169
             :||..|.....| |.:.|..::|.|       .|.::....||:.||.       |:| |..:.
  Rat   125 WIGYGLLLLNGQP-WFQHRRMLTPAF-------HYDILKPYVKNMADSIRLMLDKWEQLAGQDSS 181

  Fly   170 VQVKDLCSRFTTDLIATIAFG------VEAN------ALQDAKSEF-------FYHNRAIFSLTL 215
            :::....|..|.|.:...||.      |:.|      |:.:....|       |:.|..|::.:
  Rat   182 IEIFQHISLMTLDTVMKCAFSHNGSVQVDGNYKSYIQAIGNLNDLFHSRVRNIFHQNDTIYNFS- 245

  Fly   216 SRGIDFAIIFMIPALASLARVKLFSRETTKFIRSSVNYVLKER----ERTGE-------KRNDLI 269
            |.|                  .||:| ..:......:.|:|.|    :..||       :|.|.:
  Rat   246 SNG------------------HLFNR-ACQLAHDHTDGVIKLRKDQLQNAGELEKVKKKRRLDFL 291

  Fly   270 DILLALKREAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQE 334
            ||||..:.|   |...:|   |.| |.|:...|...|.:|:||.::...|.||.:...|.|.|:|
  Rat   292 DILLLARME---NGDSLS---DKD-LRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREE 349

  Fly   335 IVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPF-HNMELPH 398
            :....||...|:::.:.::||.:..:.|.||.||.|..|.||.|        |...| ....||.
  Rat   350 VQSVLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELS--------TSVTFPDGRSLPK 406

  Fly   399 GMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLG 463
            |:.:.:|...:|.:|:.||:||.:||.||...:..:.:  :::||..|.|||||.:..:  |::.
  Rat   407 GIQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSH--SFLPFSGGARNCIGKQFAM--SEMK 467

  Fly   464 LVHILRNHRFHTC-DKTIKKIEWAPTSPVMASKRDIILRVEKV 505
            ::..|...||... |.|  |:.......|:.||..|.|.::|:
  Rat   468 VIVALTLLRFELLPDPT--KVPIPLPRLVLKSKNGIYLYLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	120/480 (25%)
Cyp4a1	NP_787031.1	CYP4B-like	71..504	CDD:410771	122/492 (25%)