Protein Alignment Cyp6w1 and Cyp3a73

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: XP_038945885.1
• Gene: Cyp3a73 / 498198
• RGDID: 1595705
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 522
• Identity: 146/522 - (27%)
• Similarity: 263/522 - (50%)
• Gaps: 59/522 - (11%)

  Fly     5 LLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPFFEQIQKFHEAPGFENEP 69
            |||..:.::||.:..||...:::.|:...:|.|       ||...:.::..:.||......:...
  Rat    13 LLLAIILVLFYRFGTRTHGIFKKQGIPGPKPLP-------FLGTVLNYYRGLWKFDMECYKKCGK 70

  Fly    70 FVGVYMTHRPALVIRDLELIKTVMIKK-FQYFNNRVLQTDPHNDALGY--KNLFFARSPGWRELR 131
            ..|::....|...|.|.|:||:|::|: |..|.||     .:...:|.  |::..|:...|:..|
  Rat    71 IWGLFDGQTPVFAIMDTEMIKSVLVKECFSVFTNR-----RNIGPVGIMSKSISVAKDEEWKRYR 130

  Fly   132 TKISPVFTSGKIKQMYPLMVKIG----KNLQDSAERLGSGTEVQVKDLCSRFTTDLIATIAFGVE 192
            ..:||.||||::|:|:|::...|    |.|:...|:   |..:.:|::...::.|:|.:.:|.|.
  Rat   131 AFLSPTFTSGRLKEMFPIIEHYGDILVKYLKQKVEK---GKPLAMKEVFGAYSMDVITSTSFEVN 192

  Fly   193 ANALQDAKSEFFYHNRAIFSLTLSRGIDF-------AIIF-MIPALASLARVKLFSRETTKFIRS 249
            .|::.:.|..|      :..:...:..||       .::| .:..:..:..:.||.:::..|.:.
  Rat   193 INSINNPKDPF------VEKVKKFQRFDFFDPLFLSVVLFPFLTPIYEMLNICLFPKDSVAFFQK 251

  Fly   250 SVNYVLKERERTGEKRNDLIDILLALKREAAANPGKMSKEV--DLDYLVAQAAVFQTAGFETSAS 312
            .| |.:|: .|...|....:|.|..:......:..|:|.:.  |:: :||||.:|..|.:||::|
  Rat   252 FV-YRMKQ-TRLDSKHKHRVDFLQLMMNAHNNSKDKVSHKALSDIE-IVAQAIIFIFASYETTSS 313

  Fly   313 TMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGY-IERE 376
            |::..||.||.:...|.:|::||.....::...:|:.:.||.||..|:|||.|.||| || :||.
  Rat   314 TLSFVLYSLATHPDSQKKLQEEIDRALPNKAPPTYDTVMEMEYLDMVLNETPRLYPI-GYRLERV 377

  Fly   377 CSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYM 441
            |.:..:        ...:.:|.|..:.:....:..|||:||:||::.||||:..|:.:::...|:
  Rat   378 CKKDIK--------LDGVFIPKGSVVMIPFYTLQHDPQHWPEPEEFLPERFSKENKGSIDPYVYL 434

  Fly   442 PFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIE------WAPTSPVMAS--KRDI 498
            |||.|||||||||..|:..||.|..:|:|..|..|::|...::      :.|..|::..  .||.
  Rat   435 PFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQLCEETQIPLKLSRQRLFGPEKPIVLKVVPRDA 499

  Fly   499 IL 500
            ::
  Rat   500 VI 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	131/456 (29%)
Cyp3a73	XP_038945885.1	CYP3A	67..493	CDD:410743	130/451 (29%)