Protein Alignment Cyp6w1 and cyp-25A3

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001040850.1
• Gene: cyp-25A3 / 4363046
• WormBaseID: WBGene00014697
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 491
• Identity: 133/491 - (27%)
• Similarity: 240/491 - (48%)
• Gaps: 53/491 - (10%)

  Fly     1 MLLLLLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFP--VVGCTREFLTAKVPF-----FEQIQK 58
            :|..:|:..::.:.|:...|...|..|..:....|.|  ::|..::.:..|...     ::...|
 Worm     5 ILTSILVSLVSFIIYVILARKERFRLRGKIGLSGPEPHWLMGNLKQIIERKAKLGYDDSYDWYNK 69

  Fly    59 FHEAPGFENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNR----VLQTDPHNDALGYKNL 119
            .|:..|   |.| |:|...:..:.|.:.|.||.|.||.|..|::|    :::.:...::| .:|.
 Worm    70 LHKQFG---ETF-GIYFGTQLNINITNEEDIKEVFIKNFSNFSDRTPPPIIEDNKLKESL-LQNT 129

  Fly   120 FFARSPGWRELRTKISPVFTSGKIKQMY-PLMVKIGKNLQDSAERLGSGTEVQVKDLCSRFTTDL 183
            :   ..||:..|:.|:|:|::||:|.|: .:..|:...|:...|:..||.:..:.|.....|.|:
 Worm   130 Y---ESGWKHTRSAIAPIFSTGKMKAMHETIHSKVDLFLEILKEKASSGQKWDIYDDFQGLTLDV 191

  Fly   184 IATIAFGVEANALQDAKSEFFYHN--RAIFSLTLSRGIDFAIIFMIPALASLARVKLFSRETTKF 246
            |...||.:::|..:| :::.||.|  :.|.::.:......:..|:.|.|:.|.:| |:  ..|..
 Worm   192 IGKCAFAIDSNCQRD-RNDVFYVNARKFITNIDIRHSKIISTSFLFPELSKLWKV-LY--RFTDL 252

  Fly   247 IRSSVNYV-----LKERERTGEKRNDLIDIL-LALKREAAANPGKMSKEVDLDYLVAQAAVFQTA 305
            .::.:..|     :.||.|.|| .:|.:|:| |.|.||     ...||.:....::.....|..|
 Worm   253 AKAEIPLVEGLADVYERRRGGE-GSDSVDLLKLLLNRE-----DDKSKPMTKQEVIENCFAFLLA 311

  Fly   306 GFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKY-PI 369
            |:||:::.||...|.|:|...:|.:|.:||:: ..:...::|:.|..|.||..|..||||.| |:
 Worm   312 GYETTSTAMTYCSYLLSKYPNVQQKLYEEIME-AKENGGLTYDSIHNMKYLDYVYKETLRCYPPV 375

  Fly   370 VGYIERECSQ--PAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNR 432
            :.:..|.|.:  ...|:.:          |.|..:......|||:|:.|..||::.||||.:...
 Worm   376 IHFSNRRCLKDITIRGQFY----------PKGAIVVCLPHTVHRNPENWDSPEEFHPERFENWEE 430

  Fly   433 DNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHIL 468
            .:.:: .::|||||||.|:|||...::.|..:..:|
 Worm   431 KSSSL-KWIPFGVGPRYCVGMRFAEMEFKTTIAKLL 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	120/418 (29%)
cyp-25A3	NP_001040850.1	CYP3A-like	73..495	CDD:410678	121/423 (29%)