Protein Alignment Cyp6w1 and Cyp6a18

DIOPT Version :9

• Sequence 1: NP_001286145.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Alignment Length: 516
• Identity: 181/516 - (35%)
• Similarity: 294/516 - (56%)
• Gaps: 27/516 - (5%)

  Fly     2 LLLLLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPFFEQIQKFHEAPGFE 66
            |..:.:..|.||.||..|: |::::|.|:.|.:|.|:.|....:...:. ..|..|:::......
  Fly     7 LFQVAVALLAIVTYILHRK-LTYFKRRGIPYDKPHPLRGNMEGYKKTRT-VHEIHQEYYNKYRNS 69

  Fly    67 NEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDALGYKNLFFARSPGWRELR 131
            ..||||.|:..:||..:.||||.|.::||.|..|.::.:..:..:|.:. .:||....|.||.||
  Fly    70 KAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMS-AHLFNLDGPQWRLLR 133

  Fly   132 TKISPVFTSGKIKQMYPLMVKIGKN-LQDSAERLGSGTEVQVKDLCSRFTTDLIATIAFGVEANA 195
            :|:|..|||||:|.|||.:|.:.:. :....|::...:.:.|:||.:|||.|:|.|.|||::.|:
  Fly   134 SKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFGIKCNS 198

  Fly   196 LQDAKSEFFYHNRAIFSLTLSRGIDFAIIFMIPALASLARVKLFSRETTKFIRSSVNYVLKE--- 257
            |:|.|:||.:..|.  :|..||..:. :..::.:..:|||.....|.|.: |:.....::||
  Fly   199 LRDEKAEFLHFGRR--ALLDSRHGNL-VSGLMRSYPNLARRLGLCRNTAQ-IQEFYQRIVKETVT 259

  Fly   258 -RERTGEKRNDLIDILLALK--REAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLY 319
             ||:...||||.:|:|:.||  :......|::.|.:.:|.:||||.||..|||:||:|||...||
  Fly   260 LREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALY 324

  Fly   320 ELAKNEALQDRLRQEIVDFFGDEDH-ISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEG 383
            |||||.::||::|.|:.......|. .:||.|:::.||.||:|||||.|.||..::|     ...
  Fly   325 ELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDR-----VAA 384

  Fly   384 ERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFN---SSNRDNLNMDAYMPFGV 445
            :||.:.......:..|.|:.:.:.|:|.||..:|:|.::.||||:   |:.|.::   |::|||.
  Fly   385 KRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSV---AWLPFGE 446

  Fly   446 GPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIEWAPTSPVMAS-KRDIILRVEKV 505
            |||||||:|.|.:|:::||..:::|..|..|..|...:.:.|.|.::.. |..|.|:||.:
  Fly   447 GPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLGIKGGIQLKVEAI 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_001286145.1	p450	34..501	CDD:278495	167/478 (35%)
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	168/479 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461126
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	11	10.800