Protein Alignment Cyp6w1 and Cyp6a8

DIOPT Version :9

• Sequence 1: NP_001286145.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 187/520 - (35%)
• Similarity: 292/520 - (56%)
• Gaps: 47/520 - (9%)

  Fly     6 LLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAK---VPFFEQIQKFHEAPGFEN 67
            ||..||  :||  .|.|::::|.|:.::.|..:.|...|....|   ..|.:...||.|:    .
  Fly    14 LLAILT--YYI--HRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRES----K 70

  Fly    68 EPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDALGYKNLFFARSPGWRELRT 132
            .||||.:....||..:.||||.|.::||.|..|:|:.:..:..:|.:. .:||......||.||.
  Fly    71 APFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPIS-AHLFNLDGAQWRLLRN 134

  Fly   133 KISPVFTSGKIKQMYPLMVKIGKNLQD-SAERLGSGTEVQVKDLCSRFTTDLIATIAFGVEANAL 196
            |:|..|||||:|.|||.:|.:...... ..|::...:.::::||.:|||.|:|.|.|||::.|:|
  Fly   135 KLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIGTCAFGIQCNSL 199

  Fly   197 QDAKSEFFYHNRAIFSL------TLSRGIDFAIIFMIPALASLARVKLFSRETTKFIRSSVNYVL 255
            :|.|:||.|..:.  ||      ||..|      || .:...||| ||....|...|:...:.::
  Fly   200 RDEKAEFLYFGKR--SLVDKRHGTLLNG------FM-RSYPKLAR-KLGMVRTAPHIQEFYSRIV 254

  Fly   256 KE----RERTGEKRNDLIDILLALK--REAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTM 314
            .|    ||:...||||.:|:|:.||  :|.....|.:.:.:.::.::|||.||..||||||:|||
  Fly   255 TETVAVREKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTM 319

  Fly   315 TMTLYELAKNEALQDRLRQEIVDFFGDED-HISYERIQEMPYLSQVVNETLRKYPIVGYIERECS 378
            ...|||||||..:||::|.|:.:.....| :.:||..:::.||:||::||||.|.||..::|..:
  Fly   320 GFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAA 384

  Fly   379 QPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFN---SSNRDNLNMDAY 440
                 :|:.:....|..:..|.|:.:.:.|:|.||..:|:|.::.||||:   |:.|.::   |:
  Fly   385 -----KRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSV---AW 441

  Fly   441 MPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIEWAPTSPVMASKRDIILRVEKV 505
            :|||.|||||||:|.|.:|:::||..::||.:|.||.||...:.:.|.|.|:..|..|.|:||.|
  Fly   442 LPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKVETV 506

  Fly   506  505
              Fly   507  506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_001286145.1	p450	34..501	CDD:278495	173/486 (36%)
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	174/486 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461127
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	11	10.800