Protein Alignment Cyp6w1 and Cyp26b1

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_851601.2
• Gene: Cyp26b1 / 312495
• RGDID: 631379
• Length: 512
• Species: Rattus norvegicus
• Alignment Length: 535
• Identity: 123/535 - (22%)
• Similarity: 204/535 - (38%)
• Gaps: 121/535 - (22%)

  Fly     3 LLLLLGSLTIVF----YIWQRRTLSFWERHGVKYIR--------PFPVVGCTREFLTAKVPFFEQ 55
            |...|.|:|::.    .:||.|    |.....|..:        .||::|.|..:|.
  Rat    15 LAACLVSVTLLLAVSQQLWQLR----WAATRDKSCKLPIPKGSMGFPLIGETGHWLL-------- 67

  Fly    56 IQKFHEAPGFEN---EPFVGVYMTH---RPALVIRDLELIKTVMIKKFQYFNN------RVLQTD 108
                 :..||::   |.:..|:.||   ||.:.:...|.::.:::.:.|..:.      |||
  Rat    68 -----QGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILLGEHQLVSTEWPRSARVL--- 124

  Fly   109 PHNDALGYKNLFFARSPG--WRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSAERLGSGTE-V 170
                 ||...:  |.|.|  .|..|...|.:|:...::...|   ||...:||:.....|..| :
  Rat   125 -----LGPNTV--ANSIGDIHRNKRKVFSKIFSHEALESYLP---KIQLVIQDTLRAWSSQPEAI 179

  Fly   171 QVKDLCSRFTTDLIATIAFGVEANALQDAKSEF-----FYHNRAIFSLTLS-------RGIDFAI 223
            .|.....|.|..:...:..|..... :|..:.|     |..|  :|||.:.       |||.
  Rat   180 NVYQEAQRLTFRMAVRVLLGFSIPE-EDLGNLFEVYQQFVEN--VFSLPVDLPFSGYRRGIQ--- 238

  Fly   224 IFMIPALASLARVKLFSRETTKFIRSSVNYVLKERERTGEKRNDLIDILLALKREAAANPGKMSK 288
                      || ::..:...|.||..:...      .|:..:|.:|||:...:|       ..|
  Rat   239 ----------AR-QILQKGLEKAIREKLQCT------QGKDYSDALDILIESSKE-------HGK 279

  Fly   289 EVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVD---FFGD----EDHIS 346
            |:.:..|.........|.:.|:||..|..:.:|.|:.|:.::||:|:..   ..|.    |..:.
  Rat   280 EMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPAVLEKLREELRAQGLLHGGGCPCEGTLR 344

  Fly   347 YERIQEMPYLSQVVNETLRKY-PIVGYIERECSQPAEGERFTLEPFH--NMELPHGMSIYMSTVA 408
            .:.:..:.||..|:.|.:|.: |:.|           |.|..|:.|.  ..::|.|.|:..|...
  Rat   345 LDMLSGLRYLDCVIKEVMRLFTPVSG-----------GYRTVLQTFELDGFQIPKGWSVMYSIRD 398

  Fly   409 VHRDPQYWPDPEKYDPERFNSS-NRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHR 472
            .|.....:.|...:||:||:.: :.|......|:|||.|.|.|:|..|..|..|:..|.:....|
  Rat   399 THDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSR 463

  Fly   473 FHTCDKTIKKIEWAP 487
            |....:|..:|...|
  Rat   464 FELATRTFPRITLVP 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	107/459 (23%)
Cyp26b1	NP_851601.2	CYP26B1	60..490	CDD:410730	112/486 (23%)