Protein Alignment Cyp6w1 and Cyp4a3

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 567
• Identity: 129/567 - (22%)
• Similarity: 224/567 - (39%)
• Gaps: 142/567 - (25%)

  Fly     1 MLLLLLLGSLTIVFYI---WQRRTL-------SFW-ERHGVKYIRPFPVVGCTREF---LTAKVP 51
            :|.|.|:....:.||:   |..:.|       |.| ..|.:|          .|||   ||
  Rat    24 LLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHDLK----------DREFQQVLT---- 74

  Fly    52 FFEQIQKFHEAPGFENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDAL-- 114
               .::||   ||...:...|    .:..:::.|.:.:|.|:.:           :||....:
  Rat    75 ---WVEKF---PGACLQWLSG----SKTRVLLYDPDYVKVVLGR-----------SDPKASGIYQ 118

  Fly   115 ----------GYKNLFFARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSAERLGSGTE 169
                      || .|.......|.:....::|.|..|.:|....:|......:.|..|:|.....
  Rat   119 FLAPWIVSGTGY-GLLLLNGKKWFQHWRMLTPAFHYGILKPYVKIMADSVSIMLDKWEKLDDQDH 182

  Fly   170 -VQVKDLCSRFTTDLIATIAFGVEAN------------ALQDAKSEFFYHNRAIFSLTLSRGIDF 221
             :::....|..|.|.:...||..:.:            |::|..:..|:..|:.|       ...
  Rat   183 PLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLTFFRVRSAF-------YGN 240

  Fly   222 AIIFMIPALASLARVKLFSRETTKFIRSSVNYVLK----------ERERTGEKRN-DLIDILLAL 275
            :||:.:.:...|      ||...:......:.|:|          |.::..:||: |.:||||..
  Rat   241 SIIYNMSSDGRL------SRRACQIAHEHTDGVIKMRKAQLQNEEELQKARKKRHLDFLDILLFA 299

  Fly   276 KREAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFG 340
            |.|    .||...:.||.   |:...|...|.:|:||.::...|.||.:...|:|.|:|:....|
  Rat   300 KME----DGKSLSDEDLR---AEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILG 357

  Fly   341 DEDHISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPA---EGERFTLEPFHNMELPHGMSI 402
            |...::::.:.::.|.:..:.|.||.||.|..:.||.|.|.   :|.          .:|.|::.
  Rat   358 DGTSVTWDHLDQISYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGR----------SIPKGITT 412

  Fly   403 YMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHI 467
            .:....:|.:|.|||:|:.:||.||:..:..:.:  ||:||..|.|||||.:..:.:.|:.:.
  Rat   413 TILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSH--AYLPFSGGARNCIGKQFAMNELKVAVA-- 473

  Fly   468 LRNHRFHTCDKTIKKIEWAPTSP---------VMASKRDIILRVEKV 505
                      .|:.:.|..|...         |:.||..|.||::|:
  Rat   474 ----------LTLLRFELLPDPTRIPVPMARLVLKSKNGIHLRLKKL 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	105/478 (22%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	113/506 (22%)