Protein Alignment Cyp6w1 and Cyp3a2

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: XP_063127162.1
• Gene: Cyp3a2 / 266682
• RGDID: 708379
• Length: 505
• Species: Rattus norvegicus
• Alignment Length: 516
• Identity: 144/516 - (27%)
• Similarity: 261/516 - (50%)
• Gaps: 51/516 - (9%)

  Fly     5 LLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPF-FEQIQKFHEAPGFENE 68
            :||..:.::.|.........:::.|:...:|.|.:|....:......| .|..:|:.:
  Rat    13 VLLAVILVLLYRLGTHRHGIFKKQGIPGPKPLPFLGTVLNYYKGLGRFDMECYKKYGK------- 70

  Fly    69 PFVGVYMTHRPALVIRDLELIKTVMIKK-FQYFNNRVLQTDPHNDALGYKNLFFARSPGWRELRT 132
             ..|::....|...|.|.|:||.|::|: |..|.||   .|.....:..|.:..|:...|:..|.
  Rat    71 -IWGLFDGQTPVFAIMDTEMIKNVLVKECFSVFTNR---RDFGPVGIMGKAVSVAKDEEWKRYRA 131

  Fly   133 KISPVFTSGKIKQMYPLMVKIG----KNLQDSAERLGSGTEVQVKDLCSRFTTDLIATIAFGVEA 193
            .:||.||||::|:|:|::.:.|    |.|:..||   :|..|.:|.:...::.|:|.:.:|||..
  Rat   132 LLSPTFTSGRLKEMFPIIEQYGDILVKYLKQEAE---TGKPVTMKKVFGAYSMDVITSTSFGVNV 193

  Fly   194 NALQDAKSEFFYHNRAIFSLTLSRGIDFAII---FMIPALASLARVKLFSRETTKFIRSSVNYVL 255
            ::|.:.|..|....:.:........:..:::   |:.| :..:..:.:|.:::..|.:..|:.:.
  Rat   194 DSLNNPKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTP-IYEMLNICMFPKDSIAFFQKFVHRIK 257

  Fly   256 KERERTGEK--RNDLIDILLALKREAAANPGKMSKE-------VDLDYLVAQAAVFQTAGFETSA 311
            :.|..:..|  |.|.:.::|        |....||:       .|:: ::||:.:|..||:||::
  Rat   258 ETRLDSKHKVHRVDFLQLML--------NAHNNSKDEVSHKALSDVE-IIAQSVIFIFAGYETTS 313

  Fly   312 STMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYIERE 376
            ||::..||.||.:..:|.:|::||......:...:|:.:.||.||..|:|||||.|||...:||.
  Rat   314 STLSFVLYFLATHPDIQKKLQEEIDGALPSKAPPTYDIVMEMEYLDMVLNETLRLYPIGNRLERV 378

  Fly   377 CSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYM 441
            |.:..|        ...:.:|.|..:.:.|.|:|.|||:||.||::.||||:..|:.:::...|:
  Rat   379 CKKDIE--------LDGLFIPKGSVVTIPTYALHHDPQHWPKPEEFHPERFSKENKGSIDPYVYL 435

  Fly   442 PFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIEWAPTSPVMASKRDIILRV 502
            |||.|||||||||..|:..||.|..:|:|..|..|.:|...::.: ...::..::.|:|:|
  Rat   436 PFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLS-RQAILEPEKPIVLKV 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	131/447 (29%)
Cyp3a2	XP_063127162.1	None