Protein Alignment Cyp6w1 and Cyp26b1

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_780684.1
• Gene: Cyp26b1 / 232174
• MGIID: 2176159
• Length: 512
• Species: Mus musculus
• Alignment Length: 535
• Identity: 121/535 - (22%)
• Similarity: 204/535 - (38%)
• Gaps: 121/535 - (22%)

  Fly     3 LLLLLGSLTIVF----YIWQRRTLSFWERHGVKYIR--------PFPVVGCTREFLTAKVPFFEQ 55
            |...|.|:|::.    .:||.|    |.....|..:        .||::|.|..:|.
Mouse    15 LAACLVSVTLLLAVSQQLWQLR----WAATRDKSCKLPIPKGSMGFPLIGETGHWLL-------- 67

  Fly    56 IQKFHEAPGFEN---EPFVGVYMTH---RPALVIRDLELIKTVMIKKFQYFNN------RVLQTD 108
                 :..||::   |.:..|:.||   ||.:.:...|.::.:::.:.|..:.      |||
Mouse    68 -----QGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILLGEHQLVSTEWPRSARVL--- 124

  Fly   109 PHNDALGYKNLFFARSPG--WRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSAERLGSGTE-V 170
                 ||...:  |.|.|  .|..|...|.:|:...::...|   ||...:||:.....|..| :
Mouse   125 -----LGPNTV--ANSIGDIHRNKRKVFSKIFSHEALESYLP---KIQLVIQDTLRAWSSQPEAI 179

  Fly   171 QVKDLCSRFTTDLIATIAFGV-----EANALQDAKSEFFYHNRAIFSLTLS-------RGIDFAI 223
            .|.....|.|..:...:..|.     :...|.:...:|..:   :|||.:.       |||.
Mouse   180 NVYQEAQRLTFRMAVRVLLGFSIPEEDLGHLFEVYQQFVEN---VFSLPVDLPFSGYRRGIQ--- 238

  Fly   224 IFMIPALASLARVKLFSRETTKFIRSSVNYVLKERERTGEKRNDLIDILLALKREAAANPGKMSK 288
                      || ::..:...|.||..:...      .|:..:|.:|||:...:|       ..|
Mouse   239 ----------AR-QILQKGLEKAIREKLQCT------QGKDYSDALDILIESSKE-------HGK 279

  Fly   289 EVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVD---FFGD----EDHIS 346
            |:.:..|.........|.:.|:||..|..:.:|.|:.|:.::||:|:..   ..|.    |..:.
Mouse   280 EMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPAVLEKLREELRAQGLLHGGGCPCEGTLR 344

  Fly   347 YERIQEMPYLSQVVNETLRKY-PIVGYIERECSQPAEGERFTLEPFH--NMELPHGMSIYMSTVA 408
            .:.:..:.||..|:.|.:|.: |:.|           |.|..|:.|.  ..::|.|.|:..|...
Mouse   345 LDTLSSLRYLDCVIKEVMRLFTPVSG-----------GYRTVLQTFELDGFQIPKGWSVMYSIRD 398

  Fly   409 VHRDPQYWPDPEKYDPERFNSS-NRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHR 472
            .|.....:.|...:||:||:.: :.|......|:|||.|.|.|:|..|..|..|:..|.:....|
Mouse   399 THDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSR 463

  Fly   473 FHTCDKTIKKIEWAP 487
            |....:|..:|...|
Mouse   464 FELATRTFPRITLVP 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	105/459 (23%)
Cyp26b1	NP_780684.1	CYP26B1	60..490	CDD:410730	110/486 (23%)