Protein Alignment Cyp6w1 and cyp-13A2

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 142/544 - (26%)
• Similarity: 247/544 - (45%)
• Gaps: 111/544 - (20%)

  Fly     5 LLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVP----FFEQIQKFHEAPGF 65
            :.||.||...:||     ::|.|.|||..|..|.||.....|..:.|    ..|..:|:.:..|:
 Worm    13 IFLGILTYYLWIW-----TYWMRKGVKGPRGRPFVGVLDVLLEHETPGLIKLGEWTKKYGKVYGY 72

  Fly    66 ENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVL---QTDPHND-------ALGYKNLF 120
            .:    |...|    ||:.|..::..:.:|:|..|..|.|   |.:|..:       |.||:
 Worm    73 TD----GTQRT----LVVADPAMVHEIFVKQFDNFYGRKLNPIQGNPEKEQRVHLLAAQGYR--- 126

  Fly   121 FARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSA--------ERLGSGTEVQVKDLCS 177
                  |:.|||..|..|::..:|       |:.:.::|||        ::...|.::.:.....
 Worm   127 ------WKRLRTISSQSFSNASLK-------KMKRTVEDSALELLRHIEKQTAGGEQIDMLRFYQ 178

  Fly   178 RFTTDLIATIAFG-----VEANALQDAKSEFFYHNRAIFSLTLSRGIDFAIIFMIPALASLAR-- 235
            .:|.|:|...|.|     :..|.:.:...|.|..:|....|         |..:.|.:....|
 Worm   179 EYTMDVIGRFAMGQTDSMMFKNPIVNVVREIFCGSRKNLML---------ICQVFPPIGQFIRDL 234

  Fly   236 ---------VKLFSRETTKFIRSSVNYVLKERER-----TGE----------KRNDLIDILLALK 276
                     .||:|     .::..|...:.:|||     :||          .|:|.:|.....:
 Worm   235 TFKFPRIPAFKLYS-----IMQDVVAARIAQREREKGAESGEPQDFIDLFLDARSDDVDFSAEAR 294

  Fly   277 REAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGD 341
            .:.:....|::||:..|.:|.|..:|...||:|:|.:::...|.||.|..:|:::.:||...||.
 Worm   295 EDFSKRNLKITKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREFGT 359

  Fly   342 EDHISYERIQEMPYLSQVVNETLRKYPIVGYI-ERECSQPAEGERFTLEPFHNMELPHGMSIYMS 405
            .: :.:|::..:.|:..|:.|.||.||:.... .|:|.:..        ..:.:::..|:.:.|.
 Worm   360 SE-VEFEKLGRLKYMDCVIKEALRLYPLASISNSRKCMKTT--------TVNGVKIEAGVYVQMD 415

  Fly   406 TVAVHRDPQYW-PDPEKYDPERFNSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILR 469
            |.::|.||:.| .|.:::.|||: |::....:..||:|||:|||.||||||.:::.|:.|.|:|:
 Worm   416 TWSLHYDPELWGEDVKEFKPERW-STDEPLEHKGAYLPFGLGPRQCIGMRLAIMEQKILLTHLLK 479

  Fly   470 NHRFHTCDKT---IKKIEWAPTSP 490
            |:.|.|.:||   :|.:..|.|||
 Worm   480 NYTFETGNKTRIPLKLVGSATTSP 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	122/478 (26%)
cyp-13A2	NP_496109.1	CYP3A-like	65..508	CDD:410678	124/487 (25%)