Protein Alignment Cyp6w1 and cyp-13A2

DIOPT Version :9

• Sequence 1: NP_001286145.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 142/544 - (26%)
• Similarity: 247/544 - (45%)
• Gaps: 111/544 - (20%)

  Fly     5 LLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVP----FFEQIQKFHEAPGF 65
            :.||.||...:||     ::|.|.|||..|..|.||.....|..:.|    ..|..:|:.:..|:
 Worm    13 IFLGILTYYLWIW-----TYWMRKGVKGPRGRPFVGVLDVLLEHETPGLIKLGEWTKKYGKVYGY 72

  Fly    66 ENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVL---QTDPHND-------ALGYKNLF 120
            .:    |...|    ||:.|..::..:.:|:|..|..|.|   |.:|..:       |.||:
 Worm    73 TD----GTQRT----LVVADPAMVHEIFVKQFDNFYGRKLNPIQGNPEKEQRVHLLAAQGYR--- 126

  Fly   121 FARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSA--------ERLGSGTEVQVKDLCS 177
                  |:.|||..|..|::..:|       |:.:.::|||        ::...|.::.:.....
 Worm   127 ------WKRLRTISSQSFSNASLK-------KMKRTVEDSALELLRHIEKQTAGGEQIDMLRFYQ 178

  Fly   178 RFTTDLIATIAFG-----VEANALQDAKSEFFYHNRAIFSLTLSRGIDFAIIFMIPALASLAR-- 235
            .:|.|:|...|.|     :..|.:.:...|.|..:|....|         |..:.|.:....|
 Worm   179 EYTMDVIGRFAMGQTDSMMFKNPIVNVVREIFCGSRKNLML---------ICQVFPPIGQFIRDL 234

  Fly   236 ---------VKLFSRETTKFIRSSVNYVLKERER-----TGE----------KRNDLIDILLALK 276
                     .||:|     .::..|...:.:|||     :||          .|:|.:|.....:
 Worm   235 TFKFPRIPAFKLYS-----IMQDVVAARIAQREREKGAESGEPQDFIDLFLDARSDDVDFSAEAR 294

  Fly   277 REAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGD 341
            .:.:....|::||:..|.:|.|..:|...||:|:|.:::...|.||.|..:|:::.:||...||.
 Worm   295 EDFSKRNLKITKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREFGT 359

  Fly   342 EDHISYERIQEMPYLSQVVNETLRKYPIVGYI-ERECSQPAEGERFTLEPFHNMELPHGMSIYMS 405
            .: :.:|::..:.|:..|:.|.||.||:.... .|:|.:..        ..:.:::..|:.:.|.
 Worm   360 SE-VEFEKLGRLKYMDCVIKEALRLYPLASISNSRKCMKTT--------TVNGVKIEAGVYVQMD 415

  Fly   406 TVAVHRDPQYW-PDPEKYDPERFNSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILR 469
            |.::|.||:.| .|.:::.|||: |::....:..||:|||:|||.||||||.:::.|:.|.|:|:
 Worm   416 TWSLHYDPELWGEDVKEFKPERW-STDEPLEHKGAYLPFGLGPRQCIGMRLAIMEQKILLTHLLK 479

  Fly   470 NHRFHTCDKT---IKKIEWAPTSP 490
            |:.|.|.:||   :|.:..|.|||
 Worm   480 NYTFETGNKTRIPLKLVGSATTSP 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_001286145.1	p450	34..501	CDD:278495	131/515 (25%)
cyp-13A2	NP_496109.1	p450	35..511	CDD:278495	131/517 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.760