Protein Alignment Cyp6w1 and cyp-13A5

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_496112.1
• Gene: cyp-13A5 / 188356
• WormBaseID: WBGene00011672
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 147/554 - (26%)
• Similarity: 256/554 - (46%)
• Gaps: 110/554 - (19%)

  Fly     7 LGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPFFEQIQKFHEAPGF------ 65
            :|.||...:||     |||.|.|||..|.||..|...||            :.:|.||.
 Worm    13 IGLLTYYIWIW-----SFWIRKGVKGPRGFPFFGVIHEF------------QDYENPGLLKLGEW 60

  Fly    66 --ENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNR---VLQTDPHNDALGYKNLFFARSP 125
              |..|..|:.......|::.:.|.:..|.:|:|..|..|   .:|.||:.:...:  |..|:..
 Worm    61 TKEYGPIYGITEGVEKTLIVSNPEFVHEVFVKQFDNFYGRKTNPIQGDPNKNKRAH--LVSAQGH 123

  Fly   126 GWRELRTKISPVFTSGKIKQMY----PLMVKIGKNLQDSAERLGSGTEVQVKDLCSRFTTDLIAT 186
            .|:.|||..||.|::..::::.    ..:|::.::|.|::.:   |..|.:.|....||.|:|..
 Worm   124 RWKRLRTLSSPTFSNKNLRKIMSTVEETVVELMRHLDDASAK---GKAVDLLDYYQEFTLDIIGR 185

  Fly   187 IAFGVEANALQDAKSEFFYHN------RAIFSLTLSRGIDFAIIFMIPALASLARVKLFSR---- 241
            ||.|        ......:.|      :.||.  ..|.:.|.:..:.|...::.| :.|.|
 Worm   186 IAMG--------QTESLMFRNPMLPKVKGIFK--DGRKLPFLVSGIFPIAGTMFR-EFFMRFPSI 239

  Fly   242 ----ETTKFIRSSVNYVLKER--------ERTGEKRNDLIDILLALKREAAANP----------- 283
                :....:..::|..|::|        |.:||.: |.||:.|    :|.||.
 Worm   240 QPAFDIMSTVEKALNKRLEQRAADEKAGIEPSGEPQ-DFIDLFL----DARANVDFFEEESALGF 299

  Fly   284 -----GKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDED 343
                 .|:.|::..|.::.|..||..||::|:|.:::.:.|.||::..:|.:|::| ||......
 Worm   300 AKTEIAKVDKQLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEE-VDRECPNP 363

  Fly   344 HISYERIQEMPYLSQVVNETLRKYPIVGYI-ERECSQPAEGERFTLEPFHNMELPHGMSIYMSTV 407
            .:::::|.::.|:..||.|.||.||:...: .|:|.:    |...|    .:::..|.::.:.|.
 Worm   364 EVTFDQISKLKYMECVVKEALRMYPLASIVHNRKCMK----ETNVL----GVQIEKGTNVQVDTW 420

  Fly   408 AVHRDPQYW-PDPEKYDPERFNSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNH 471
            .:|.||:.| .|..::.|||:.|.:........|:|||:|||.||||||.:::.|:.|.|||:.:
 Worm   421 TLHYDPKVWGEDANEFRPERWESGDELFYAKGGYLPFGMGPRICIGMRLAMMEKKMLLTHILKKY 485

  Fly   472 RFHTCDKT---IKKIEWAPTSPVMASKRDIILRV 502
            .|.|..:|   :|.:..|.|:|     |.::|::
 Worm   486 TFETSTQTEIPLKLVGSATTAP-----RSVMLKL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	124/480 (26%)
cyp-13A5	NP_496112.1	CYP3A-like	63..511	CDD:410678	125/482 (26%)