Protein Alignment Cyp6w1 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 534
• Identity: 143/534 - (26%)
• Similarity: 254/534 - (47%)
• Gaps: 75/534 - (14%)

  Fly     1 MLLLLLLGSL--TIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPFFEQIQKFHEAP 63
            ::.|.:|.|:  .:.||:|   |.|:|:|.|:.....:|::|...|.|:::.|.:.|::::.:..
 Worm     3 IIFLAILTSIIGVLSFYLW---TWSYWKRRGIAGPSGYPILGSALEMLSSENPPYLQLKEWTKQY 64

  Fly    64 GFENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVL---QTDPHNDALGYKNLFFARSP 125
            |    ...|:.......|||.|.:|::.|.:|::..|..|.|   |.||:.|.  ..|||.::..
 Worm    65 G----KVYGITEGLSRTLVISDPDLVQEVFVKQYDNFFGRKLNPIQGDPNKDK--RVNLFSSQGH 123

  Fly   126 GWRELRTKISPVFTSGKIKQMYPLM----VKIGKNLQDSAERLGSGTEVQVKDLCSRFTTDLIAT 186
            .|:.|||..||.|::..::::...:    |::.::::...:   .|..:.:.|....||.|:|..
 Worm   124 RWKRLRTISSPTFSNNSLRKLKTTVEECAVELLRHIEQHTD---GGQPIDLLDFYQEFTLDVIGR 185

  Fly   187 IAFGVEANALQDAKSEFFYHNRAIF-----SLTLSRGIDFAIIFMIPALASLARVKLFSRETTKF 246
            ||.|...:  |..|:....:.||:|     .|.||..       :.|.:..:.|:.:||  ....
 Worm   186 IAMGQTDS--QMFKNPLLPYVRAVFGEPRKGLFLSGS-------LAPWIGPILRMVMFS--LPNI 239

  Fly   247 IRSSVNYVLKERERTGEKR-----------------NDLIDILLALK--------REAAANPG-K 285
            :::...:|::......|:|                 .|.||:.|..|        .|.....| |
 Worm   240 VKNPAVHVIRHTSNAVEQRVKLRMADEKAGIDPGEPQDFIDLFLDAKSDDVELENNEDFTKAGVK 304

  Fly   286 MSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERI 350
            :::::..:.:|.|..||..|||:|:|.:::.:.:.||.:..:|.:|::||.....|.: ::::::
 Worm   305 VTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDRECADPE-VTFDQL 368

  Fly   351 QEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQY 415
            .::.|:..|:.||||.||:.......|...|       ....|.|:..|.:|...|..:|.|...
 Worm   369 SKLKYMECVIKETLRMYPLGALANSRCCMRA-------TKIGNYEIDEGTNILCDTWTLHSDKSI 426

  Fly   416 W-PDPEKYDPERFNSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKT 479
            | .|.|::.|||:.|.:........|:|||:|||.||||||..::.||.|.||||.:....|:||
 Worm   427 WGEDAEEFKPERWESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHILRKYTLEVCNKT 491

  Fly   480 ---IKKIEWAPTSP 490
               :|.|....|.|
 Worm   492 QIPLKLIGSRTTQP 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	125/466 (27%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	126/471 (27%)