Protein Alignment Cyp6w1 and Cyp3a9

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 526
• Identity: 157/526 - (29%)
• Similarity: 276/526 - (52%)
• Gaps: 58/526 - (11%)

  Fly     4 LLLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPFFEQIQKFHEAPGFENE 68
            |||:.|| ::.|::...:...:::.|:...:|.|.:|   ..|..:..|:|..:..|:..|
  Rat    13 LLLVISL-VLLYLYGTHSHGIFKKLGIPGPKPLPFLG---TILAYRKGFWEFDKYCHKKYG---- 69

  Fly    69 PFVGVYMTHRPALVIRDLELIKTVMIKK-FQYFNNR-------VLQTDPHNDALGYKNLFFARSP 125
            ...|:|...:|.|.|.|.::||||::|: :..|.||       :|:          |.:..:...
  Rat    70 KLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRNFGPVGILK----------KAISISEDE 124

  Fly   126 GWRELRTKISPVFTSGKIKQMYPLMVK----IGKNLQDSAERLGSGTEVQVKDLCSRFTTDLIAT 186
            .|:.:|..:||.|||||:|:|:|::.:    :.:|::..:|   .|....:||:...::.|:|..
  Rat   125 EWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSE---EGKPTSMKDIFGAYSMDVITA 186

  Fly   187 IAFGVEANALQDAKSEFFYHNRAIFSLTLSRGIDFAIIFMIPALASL---ARVKLFSRETTKFIR 248
            .:|||..::|.:.:..|....:.:....:...: |..:.:.|.|..|   ..|.:|.|:...|.:
  Rat   187 TSFGVNVDSLNNPQDPFVEKIKKLLKFDIFDPL-FLSVTLFPFLTPLFEALNVSMFPRDVIDFFK 250

  Fly   249 SSVNYVLKERERTGEK-RNDLIDILLALKREAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSAS 312
            :||..:.:.|.:..|| |.|.:.:::..:.....:..|...:|:   :|||:.:|..||:||::|
  Rat   251 TSVERMKENRMKEKEKQRMDFLQLMINSQNSKVKDSHKALSDVE---IVAQSVIFIFAGYETTSS 312

  Fly   313 TMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYIEREC 377
            .::..||.||.:..:|.:|:.||.....::.|.:|:.:.:|.||..|||||||.|||.|.:||.|
  Rat   313 ALSFVLYLLAIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVVNETLRLYPIAGRLERVC 377

  Fly   378 SQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYMP 442
            ....|        .:.:.:|.|..:.:.|.|:|:||.|||:||::.||||:..|:||:|...|:|
  Rat   378 KTDVE--------INGVFIPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQDNINPYMYLP 434

  Fly   443 FGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIEWA------PTSPVMASKRDIILR 501
            ||.|||||||||..|:..|:.||.:|:|..|..|.:|...::.:      |..|::..   ::.|
  Rat   435 FGNGPRNCIGMRFALMNMKVALVRVLQNFSFQPCKETQIPLKLSKQGLLQPEKPLLLK---VVSR 496

  Fly   502 VEKVSG 507
            .|.|:|
  Rat   497 DETVNG 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	138/452 (31%)
Cyp3a9	NP_671739.2	CYP3A	67..492	CDD:410743	139/453 (31%)