Protein Alignment Cyp6w1 and Cyp3a62

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 519
• Identity: 159/519 - (30%)
• Similarity: 274/519 - (52%)
• Gaps: 60/519 - (11%)

  Fly     5 LLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPFFEQIQKFHEAPGFENEP 69
            :||.::.::.|::...|...:::.|:...:|.|.||   ..|..:..|:|..:..|:..|    .
  Rat    13 MLLATILVLLYLYGTSTHGNFKKLGISGPKPLPFVG---NILAYRHGFWEFDRHCHKKYG----D 70

  Fly    70 FVGVYMTHRPALVIRDLELIKTVMIKK-FQYFNNR-------VLQTDPHNDALGYKNLFFARSPG 126
            ..|.|...:|.|.|.|.::||||::|: :..|.||       :|:          |.:..:....
  Rat    71 IWGFYEGRQPILAITDPDIIKTVLVKECYSTFTNRRSFGPAGILK----------KAITLSEDEE 125

  Fly   127 WRELRTKISPVFTSGKIKQMYPLMVK----IGKNLQDSAERLGSGTEVQVKDLCSRFTTDLIATI 187
            |:.|||.:||.|||||:|:|:|::.:    :.||::..||:   |..:.:||:...::.|:|...
  Rat   126 WKRLRTLLSPTFTSGKLKEMFPIINQYADLLVKNVKHEAEK---GNPITMKDIFGAYSMDVITGT 187

  Fly   188 AFGVEANALQDAKSEFFYHNRAIFSLTLSRGID--FAIIFMIPALASLAR---VKLFSRETTKFI 247
            :|||..::|.:.::.|....:.:.....   :|  |..:.:.|.|..:..   :.:|.::..||.
  Rat   188 SFGVNVDSLNNPQNPFVQKVKKLLKFNF---LDPFFLSVILFPFLTPVFEAFDITVFPKDVMKFF 249

  Fly   248 RSSVNYVLKERERTGEKRNDLIDIL-LALKREAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSA 311
            |:||.. :|| .|..||....:|.| |.:..:::.:........|:: :|||:..|..||:||::
  Rat   250 RTSVER-MKE-NRMQEKVKQRLDFLQLMINSQSSGDKESHQGLTDVE-IVAQSIFFIFAGYETTS 311

  Fly   312 STMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYIERE 376
            |.::..||.||.:..||.:|:.||.....::..::|:.:.||.||..|:|||||.:|:.|.:||.
  Rat   312 SALSFALYLLATHPDLQKKLQDEIDAALPNKAPVTYDVLVEMEYLDMVLNETLRLFPVGGRLERV 376

  Fly   377 CSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYM 441
            |.:..|        .:.:.:|.|..:.:.|.|:|:||:.||:||::.||||...|:|::|...|:
  Rat   377 CKKDVE--------INGVFIPKGTVVMVPTFALHKDPKCWPEPEEFCPERFRKKNQDSINPYIYL 433

  Fly   442 PFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKT------IKKIEWAPTSPVM--ASKRD 497
            |||.|||||||||..|:..|:.||.:|:|..|..|.:|      .||..:.|..|::  |..||
  Rat   434 PFGNGPRNCIGMRFALMNMKIALVRVLQNFSFGLCKETQIPLKLRKKGFFQPEKPIILRAVSRD 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	145/457 (32%)
Cyp3a62	NP_001019403.1	CYP3A	67..492	CDD:410743	143/455 (31%)