Protein Alignment Cyp6w1 and Cyp26a1

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_569092.2
• Gene: Cyp26a1 / 154985
• RGDID: 620161
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 526
• Identity: 109/526 - (20%)
• Similarity: 207/526 - (39%)
• Gaps: 103/526 - (19%)

  Fly     3 LLLLLGSLTIVFYIWQRRTLSFWERHGVKYIRP----FPVVGCTREFLTAKVPFFEQIQKFHEAP 63
            |||.|.:|.    :|....:|..:|.....:.|    ||..|.|.:.:..:..|.:..::.:
  Rat    18 LLLFLAALK----LWDLYCVSSRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKY--- 75

  Fly    64 GFENEPFVGVYMTH---RPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDA-----LGYKNLF 120
            ||       :|.||   ||.:.:...:.::.:::.:     :|::..  |..|     ||...|.
  Rat    76 GF-------IYKTHLFGRPTVRVMGADNVRRILLGE-----HRLVSV--HWPASVRTILGAGCLS 126

  Fly   121 FARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSAER-LGSGTE-----VQVKDLCSRF 179
            .......::.:..|...|....::...|:   |.:.:....|: |..|..     .:||.|..|
  Rat   127 NLHDSSHKQRKKVIMQAFNREALQCYVPV---IAEEVSGCLEQWLSCGERGLLVYPEVKRLMFR- 187

  Fly   180 TTDLIATIAFGVEANALQDAKSE------FFYHNRAIFSLTLSRGIDFAIIFMIPALASLARVKL 238
               :...|..|.|.......:.|      |....|.:|||.:.  :.|:.::......:|...::
  Rat   188 ---IAMRILLGCEPGPAGGGEDEQQLVEAFEEMTRNLFSLPID--VPFSGLYRGVKARNLIHARI 247

  Fly   239 FSRETTKFIRSSVNYVLKERERTGEKRNDLIDILLALKREAAANPGKMSKEVDLDYLVAQAAVFQ 303
                 .:.||:.:..:.......|.|  |.:.:|:       .:..:..:.:|:..|...:....
  Rat   248 -----EENIRAKIRRLQAAEPDAGCK--DALQLLI-------EHSWERGERLDMQALKQSSTELL 298

  Fly   304 TAGFETSASTMTMTLYELAKNEALQDRLRQEI-----VDFFGDEDHISYERIQEMPYLSQVVNET 363
            ..|.||:||..|..:..|.....:..::|:||     :.....||.:..|.::::.|:..|:.||
  Rat   299 FGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSHHEDKLDMETLEQLKYIGCVIKET 363

  Fly   364 LRKYPIVGYIERECSQPAEGERFTLEPF--HNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPER 426
            ||..|.|         |. |.|..|:.|  :..::|.|.::..|....|.....:.:.|:::|:|
  Rat   364 LRLNPPV---------PG-GFRVALKTFELNGYQIPKGWNVIYSICDTHDVADSFTNKEEFNPDR 418

  Fly   427 FNSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCD-------KTIKKIE 484
            |.|.:.::.:..:::|||.|.|:|:|.....:..|:..|.:.|.     ||       .|:|
  Rat   419 FTSLHPEDTSRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARR-----CDWQLLNGPPTMK--- 475

  Fly   485 WAPTSP 490
               |||
  Rat   476 ---TSP 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	93/458 (20%)
Cyp26a1	NP_569092.2	cytochrome_P450	55..490	CDD:477761	98/485 (20%)