Protein Alignment Cyp6w1 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 515
• Identity: 144/515 - (27%)
• Similarity: 266/515 - (51%)
• Gaps: 45/515 - (8%)

  Fly     5 LLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPF-FEQIQKFHEAPGFENE 68
            :||....::.|.:..|....:::.|:...:|.|.:|....:......| .|..:|:.:.
Mouse    13 VLLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTVLNYYKGLWKFDMECYKKYGKT------ 71

  Fly    69 PFVGVYMTHRPALVIRDLELIKTVMIKK-FQYFNNRVLQTDPHNDALGYKNLFFARSPGWRELRT 132
              .|::....|.|.:.|.|.||.|::|: |..|.||   .|.....:..|.:..::...|:..|.
Mouse    72 --WGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNR---RDFGPVGIMSKAISISKDDEWKRYRA 131

  Fly   133 KISPVFTSGKIKQMYPLMVKIG----KNLQDSAERLGSGTEVQVKDLCSRFTTDLIATIAFGVEA 193
            .:||.|||||:|:|:|::.:.|    |.|:..|::   |..|.:||:...::.|:|.:.:|||..
Mouse   132 LLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKK---GKPVTMKDVLGAYSMDVITSTSFGVNV 193

  Fly   194 NALQDAKSEFFYHNRAIFSLTLSRGIDFAII---FMIPALASLARVKLFSRETTKFIRSSVNYVL 255
            ::|.:.:..|....:.:........:.|:::   |:.|....| .:.:|.:::.:|.:..|:. :
Mouse   194 DSLNNPEDPFVEKAKKLLRFDFFDPLLFSVVLFPFLTPVYEML-NICMFPKDSIEFFKKFVDR-M 256

  Fly   256 KERERTGEKRNDLIDILLALKREAAANPGKMSKEV--DLDYLVAQAAVFQTAGFETSASTMTMTL 318
            || .|...|:...:|.|..:......:..|:|.:.  |:: :.||:.:|..||:||::||::.||
Mouse   257 KE-SRLDSKQKHRVDFLQLMMNSHNNSKDKVSHKALSDME-ITAQSIIFIFAGYETTSSTLSFTL 319

  Fly   319 YELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEG 383
            :.||.:..:|.:|:.||.:...::...:|:.:.||.||..|:|||||.|||...:||.|.:..|
Mouse   320 HSLATHPDIQKKLQDEIDEALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIANRLERVCKKDVE- 383

  Fly   384 ERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYMPFGVGPR 448
                   .:.:.:|.|.::.:.:.|:|.|||:|.:||::.||||:..|:.:::...|:|||.|||
Mouse   384 -------LNGVYIPKGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGSIDPYVYLPFGNGPR 441

  Fly   449 NCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIEWA------PTSPVMAS--KRDIIL 500
            ||:|||..|:..||.|..|::|..|..|.:|...::.:      |..|::..  .||.::
Mouse   442 NCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLSRQGLLQPEKPIVLKVVPRDAVI 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	132/448 (29%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	132/451 (29%)