Protein Alignment Cyp6w1 and Cyp26a1

DIOPT Version :9

• Sequence 1: NP_001286145.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_031837.2
• Gene: Cyp26a1 / 13082
• MGIID: 1096359
• Length: 497
• Species: Mus musculus
• Alignment Length: 525
• Identity: 106/525 - (20%)
• Similarity: 207/525 - (39%)
• Gaps: 97/525 - (18%)

  Fly     3 LLLLLGSLTIVFYIWQRRTLSFWERHGVKYIRP----FPVVGCTREFLTAKVPFFEQIQKFHEAP 63
            |||.|.:|.    :|....:|..:|.....:.|    ||..|.|.:.:..:..|.:..::.:
Mouse    18 LLLFLAALK----LWDLYCVSSRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRRKY--- 75

  Fly    64 GFENEPFVGVYMTH---RPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDA-----LGYKNLF 120
            ||       :|.||   ||.:.:...:.::.:::.:     :|::..  |..|     ||...|.
Mouse    76 GF-------IYKTHLFGRPTVRVMGADNVRRILLGE-----HRLVSV--HWPASVRTILGAGCLS 126

  Fly   121 FARSPGWRELRTKISPVFTSGKIKQMYPLMV-KIGKNLQD--SAERLGSGTEVQVKDLCSRFTTD 182
            .......::.:..|...|:...::...|::. ::...|:.  |....|.....:||.|..|
Mouse   127 NLHDSSHKQRKKVIMQAFSREALQCYVPVIAEEVSSCLEQWLSCGERGLLVYPEVKRLMFR---- 187

  Fly   183 LIATIAFGVEANALQDAKSE------FFYHNRAIFSLTLSRGIDFAIIFMIPALASLARVKLFSR 241
            :...|..|.|.......:.|      |....|.:|||.:.  :.|:.::......:|...::...
Mouse   188 IAMRILLGCEPGPAGGGEDEQQLVEAFEEMTRNLFSLPID--VPFSGLYRGVKARNLIHARIEEN 250

  Fly   242 ETTKFIRSSVNYVLKERERTGEKRNDLIDILLALKREAAANPGKMSKEVDLDYLVAQAAVFQTAG 306
            ...|..|      |:..|..|..: |.:.:|:       .:..:..:.:|:..|...:......|
Mouse   251 IRAKIRR------LQATEPDGGCK-DALQLLI-------EHSWERGERLDMQALKQSSTELLFGG 301

  Fly   307 FETSASTMTMTLYELAKNEALQDRLRQEI-----VDFFGDEDHISYERIQEMPYLSQVVNETLRK 366
            .||:||..|..:..|.....:..::|:||     :.....::.:..|.::::.|...|:.||||.
Mouse   302 HETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSNQDNKLDMETLEQLKYTGCVIKETLRL 366

  Fly   367 YPIVGYIERECSQPAEGERFTLEPF--HNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNS 429
            .|.|         |. |.|..|:.|  :..::|.|.::..|....|.....:.:.|:::|:||..
Mouse   367 NPPV---------PG-GFRVALKTFELNGYQIPKGWNVIYSICDTHDVADIFTNKEEFNPDRFIV 421

  Fly   430 SNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCD-------KTIKKIEWAP 487
            .:.::.:..:::|||.|.|:|:|.....:..|:..|.:.|:     ||       .|:|
Mouse   422 PHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH-----CDWQLLNGPPTMK------ 475

  Fly   488 TSPVM 492
            |||.:
Mouse   476 TSPTV 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_001286145.1	p450	34..501	CDD:278495	98/494 (20%)
Cyp26a1	NP_031837.2	p450	43..491	CDD:299894	98/496 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940