Protein Alignment Cyp6w1 and Cyp4f15

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_598888.1
• Gene: Cyp4f15 / 106648
• MGIID: 2146921
• Length: 534
• Species: Mus musculus
• Alignment Length: 578
• Identity: 141/578 - (24%)
• Similarity: 225/578 - (38%)
• Gaps: 157/578 - (27%)

  Fly     2 LLLLLLG---------SLTIVFYIWQRRTLSF-----WE------------RHGVKYIRPFPVVG 40
            |||||:|         :.|.:||........|     |.            .||:|.:..
Mouse    25 LLLLLIGASWLLARVLTQTYIFYRTYHHLCDFPQPPKWNWFLGHLGMITPTEHGLKEVTN----- 84

  Fly    41 CTREFLTAKVPFFEQIQKFHEAPGFENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFN---- 101
                 |.|..|     |.|....|    |.:.:.....|.::...|....:|.:|:..:::
Mouse    85 -----LVATYP-----QGFMTWLG----PIIPIITLCHPDIIRSVLNASASVALKEVVFYSFLKP 135

  Fly   102 ---NRVLQTDPHNDALGYKNLFFARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSA-- 161
               :.:|.:|      |.|         |...|..::|.|....:|.    .|||   ..||.
Mouse   136 WLGDGLLLSD------GDK---------WSSHRRMLTPAFHFNILKP----YVKI---FNDSTNI 178

  Fly   162 -----ERLGSG--TEVQVKDLCSRFTTDLIATIAFGVEANALQDAKSEFFYHNRAIFSLTLSRGI 219
                 :.|.||  ..:.|.:..|..|.|.:....|..::|. |:..||:.   .||..|:
Mouse   179 MHAKWQHLASGGSARLDVFENISLMTLDSLQKCVFSFDSNC-QENPSEYI---SAILELS----- 234

  Fly   220 DFAIIF-----MIPALASLARVKLFSRETTK---FIRSSVNYVLKERERT--------------G 262
              |::.     ::..:.||.::....|...|   .:.|..:.|:::|.||              .
Mouse   235 --ALVTKRYHQLLLHIDSLYQLTCSGRRFHKACHLVHSFTDAVIQDRRRTLPSKHEDDVLKAKAK 297

  Fly   263 EKRNDLIDILLALKREAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEAL 327
            .|..|.||:||..|.|.       .||:..:.:.|:|..|...|.:|:||.::..||.||::...
Mouse   298 SKTLDFIDVLLLSKDED-------GKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEY 355

  Fly   328 QDRLRQEIVDFFGDEDHISYE---------RIQEMPYLSQVVNETLRKYPIVGYIERECSQP--- 380
            |:|.|||:.:...|.:....|         .:.::|:|:..:.|:||.:|.|..|.|.|:|.
Mouse   356 QERCRQEVQELLRDRESTEIECSCAVFLRDDLAQLPFLTMCIKESLRLHPPVTVISRRCTQDIVL 420

  Fly   381 AEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYMPFGV 445
            .:|.          .:|.|:...::..|.|.:|..|||||.|||.||:..|..:.:..|::||..
Mouse   421 PDGR----------VIPKGVICIINIFATHHNPTVWPDPEVYDPFRFDPENIKDRSPLAFIPFSA 475

  Fly   446 GPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIEWAPTSPVMASKRDIILRVE 503
            |||||||....:.:.|:.|...|...|....||..::            |.::|||.|
Mouse   476 GPRNCIGQTFAMNEMKVALALTLLRFRVLPDDKEPRR------------KPELILRAE 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	117/480 (24%)
Cyp4f15	NP_598888.1	CYP4F	79..527	CDD:410772	128/524 (24%)