Protein Alignment Cyp6w1 and Cyp4a32

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 573
• Identity: 141/573 - (24%)
• Similarity: 228/573 - (39%)
• Gaps: 160/573 - (27%)

  Fly     2 LLLLLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFP---------------------VVGCTREF 45
            |||||:.:  :.||:.::..|        |.::.||                     ||.|...|
Mouse    27 LLLLLVKA--VQFYLHRKWLL--------KALQQFPSPPFHWFFGHEQFKGEQELKEVVSCIEHF 81

  Fly    46 LTAKVPFFEQIQKFHEAPGFENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQTDPH 110
            .:|...:|           :.:..::.||          |.:.:|.::.:           :||.
Mouse    82 PSAFPCWF-----------WGSNAYLTVY----------DPDYMKVILGR-----------SDPK 114

  Fly   111 NDA--------LGYKNLFFARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSA------ 161
            .:.        :||..|.....| |.:.|..::|.|       .|.::....||:.||.
Mouse   115 ANGIYRLLAPWIGYGLLLLNGQP-WFQHRRMLTPAF-------HYDILKPYVKNMADSIRLMLDK 171

  Fly   162 -ERL-GSGTEVQVKDLCSRFTTDLIATIAFG------VEAN------ALQDAKSEF-------FY 205
             ||| |..:.:::....|..|.|.:...||.      |:.|      |:.|..:.|       |:
Mouse   172 WERLAGQDSSIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYKTYLQAIGDLNNLFHSRVRNIFH 236

  Fly   206 HNRAIFSLTLSRGIDFAIIFMIPALASLARVKLFSRETTKFIRSSVNYVLKERERTG---EKRND 267
            .|..|:.|: |.|          .||..| .:|....|...|:...:.:..|.|...   ::|.|
Mouse   237 QNDTIYRLS-SNG----------RLAKQA-CQLAHDHTDGVIKMRKDQLQDEGELENIKKKRRLD 289

  Fly   268 LIDILLALKREAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLR 332
            .:||||..:.|   |...||   |.| |.|:...|...|.:|:||.::...|.||.:...|.|.|
Mouse   290 FLDILLFARME---NGDSMS---DKD-LRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCR 347

  Fly   333 QEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPF-HNMEL 396
            :|:....||...|:::.:.::||.:..:.|.||.||.|..|.||.|        |...| ....|
Mouse   348 EEVQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELS--------TSVTFPDGRSL 404

  Fly   397 PHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSK 461
            |.|:.:.:|...:|.:|:.||:||.:||.||...:..:.:  :::||..|.|||||.:..:  |:
Mouse   405 PKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSH--SFLPFSGGARNCIGKQFAM--SE 465

  Fly   462 LGLVHILRNHRFHTCDKTIKKIEWAPTSP---------VMASKRDIILRVEKV 505
            |.::..|          |:...|..|...         |:.||..|.|.::|:
Mouse   466 LKVIVAL----------TLLHFELLPDPTRVPEPLARIVLKSKNGIYLHLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	121/478 (25%)
Cyp4a32	NP_001093651.1	CYP4B-like	71..504	CDD:410771	128/513 (25%)