Protein Alignment Cyp6w1 and cyp3a5

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: XP_012819594.1
• Gene: cyp3a5 / 100037874
• XenbaseID: XB-GENE-5821575
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 522
• Identity: 148/522 - (28%)
• Similarity: 263/522 - (50%)
• Gaps: 70/522 - (13%)

  Fly     3 LLLLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPFFEQIQKFHEAPGFEN 67
            ||:||.:|...:.||..:   .::|:|:....|.|.:|   .||..:          |....|:.
 Frog    14 LLVLLLTLLAYYAIWPYK---LFKRYGIPGPTPIPFIG---TFLGNR----------HGLMEFDM 62

  Fly    68 EPFV------GVYMTHRPALVIRDLELIKTVMIKK-FQYFNNRVLQTDPHNDALG---YKNLFFA 122
            |.|.      |:|...:|.|.|.|..:||::|:|: :..|.||      .:..|.   ..::..:
 Frog    63 ECFKKYGKVWGIYEGQKPLLAIVDPVIIKSIMVKECYTNFTNR------RDFGLSGPLKSSVLIS 121

  Fly   123 RSPGWRELRTKISPVFTSGKIKQMYPLMVKIG----KNLQDSAERLGSGTEVQVKDLCSRFTTDL 183
            :...|:.:||.:||.|||||:|||:|||...|    ||:.   :::.:...:.:|.:...::.|:
 Frog   122 KDEQWKRIRTVLSPTFTSGKLKQMFPLMNHYGELLVKNIH---KKINNKEPLDMKHIFGSYSMDI 183

  Fly   184 IATIAFGVEANALQDAKSEFFYHNRAIFSLTLSRGIDFAIIFMIPALASLARVKLF---SRETTK 245
            :.:.:|.|..:::.:....|..:.|.:|:.:....: |.|..:.|.|..|.....|   |.:...
 Frog   184 VLSTSFSVNVDSMNNPNDPFVTNARNLFTFSFFNPL-FLISILCPFLVPLLDKMNFCFLSLKILN 247

  Fly   246 FIRSSVNYVLKERER-TGEKRNDLIDILLALKREAAANPGKM--------SKEVDLDYLVAQAAV 301
            |.:.:|..:.|:|:: |.|.|.|.:.:::    :|.:|.||.        .||:....::||:.:
 Frog   248 FFKDAVASIKKKRQKGTHEDRVDFLQLMV----DAQSNEGKSVPEEEKHGYKELSDTEILAQSLI 308

  Fly   302 FQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRK 366
            |..||:||:::|:....|.:|.:..:|.:|.:||.....::...:|:.:.:|.|:..|:||:||.
 Frog   309 FIMAGYETTSTTLMFLAYNIATHPDVQRKLEEEIDALLPNKAPPTYDALMKMEYMDMVINESLRM 373

  Fly   367 YPIVGYIERECSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSN 431
            :|....|:|.|.:..|        .:.:.:|.|:.|.:...|:|.:|:.||:||::.||||:..|
 Frog   374 FPPAIRIDRVCKKTME--------INGVTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERFSKEN 430

  Fly   432 RDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCD------KTIKKIEWAPTSP 490
            :.|.:...::|||||||||||||..|:..|:.|..:|:|.|..||.      |...|....||.|
 Frog   431 QKNQDPYNFLPFGVGPRNCIGMRFALVNMKVALTILLQNFRLETCKDTPVPLKICTKGYLKPTKP 495

  Fly   491 VM 492
            ::
 Frog   496 II 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	132/458 (29%)
cyp3a5	XP_012819594.1	cytochrome_P450	67..498	CDD:477761	130/453 (29%)