Protein Alignment EcR and nr1i2

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_001092087.2
• Gene: nr1i2 / 565875
• ZFINID: ZDB-GENE-030903-3
• Length: 430
• Species: Danio rerio
• Alignment Length: 446
• Identity: 122/446 - (27%)
• Similarity: 217/446 - (48%)
• Gaps: 53/446 - (11%)

  Fly   224 ISSGRDDLSP-SSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGF 287
            :|...::||| ..|.:|..:.|..:.....|         :|.||||:::|||:||:||||||||
Zfish    14 MSKEMEELSPLDDSGHGDGSEEETEEDDEPK---------ICQVCGDKSTGYHFNAMTCEGCKGF 69

  Fly   288 FRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKR---REKKA 349
            |||::.:.|..||.|..||.:....||:||.|||:|||::||:.|.::.:.....:|   |.|:.
Zfish    70 FRRAMKRPAQLCCPFQSACVITKSNRRQCQSCRLQKCLSIGMKRELIMSDEAVEKRRLQIRRKRM 134

  Fly   350 QKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDL------MTCEPPQHATIPLLPDEILAKC 408
            |:|  .:|.:|.              |:.|.:|:|:.      |||   .|.: ...|.:...|.
Zfish   135 QEE--PVTLTPQ--------------QEAVIQELLNAHKKTFDMTC---AHFS-QFRPLDRGQKS 179

  Fly   409 QARNIPSLTYNQLAVIYKLI------W-YQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEI 466
            .:.:||  ..|...:.::.|      | :.......|....:.:..:....:|.:..|..|.|::
Zfish   180 VSESIP--VTNGSWIDHRPIAEDPVQWVFNSTSLSSSSSSCQSLDKEKKHFKSGSFTSLPHFTDL 242

  Fly   467 TILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDS 531
            |...::.::.|.|.|..|..:..||||:|||..:.|::::.. ..:.:....|:......|..|.
Zfish   243 TTYMIKNVINFGKTLTMFRALVMEDQISLLKGATFEIILIHF-NMFFNEVTGIWECGPLQYCMDD 306

  Fly   532 YKMAGMADNIED-LLHFCRQMFSMKVDNVEYALLTAIVIFS-DRPGLEKAQLVEAIQSYYIDTLR 594
            ...||...::.| :::|...:..:::...||.|:.|:.:|| ||||:...::::..|.....||:
Zfish   307 AFRAGFQHHLLDPMMNFHYTLRKLRLHEEEYVLMQALSLFSPDRPGVTDHKVIDRNQETLALTLK 371

  Fly   595 IYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLK-LKNRKLPKFLEEI 649
            .||..:..|...:|:| .|::..|||:|::..:..:....:: ::....|.:||.|
Zfish   372 TYIEAKRNGPEKNLLF-PKIMGCLTEMRSMNEEYTKQVLKIQDMQPEVSPLWLEII 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	43/92 (47%)
		NR_LBD_EcR	420..652	CDD:132736	54/240 (23%)
nr1i2	NP_001092087.2	NR_DBD_PXR	45..131	CDD:143536	41/85 (48%)
		NR_LBD_PXR_like	141..425	CDD:132732	66/305 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593377
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940