Protein Alignment EcR and roraa

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: XP_017209577.1
• Gene: roraa / 564951
• ZFINID: ZDB-GENE-060306-2
• Length: 519
• Species: Danio rerio
• Alignment Length: 500
• Identity: 134/500 - (26%)
• Similarity: 214/500 - (42%)
• Gaps: 97/500 - (19%)

  Fly   216 PRSDSVNSISSGRDDLSPSSSLNGYSAN---------------ESCDAKK-----SKKGPAPRVQ 260
            |.||..|.:|      .|.:.:.....|               :||.:..     :||....:::
Zfish     7 PASDPGNGVS------EPVTPVRETPVNLETLRKAEHQAPVRRQSCSSTNRGISVTKKTHTSQIE 65

  Fly   261 EELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCL 325
            ...|.:|||::||.||..:||||||||||||...:|.|.|...:.|.:|...|.:||.|||:|||
Zfish    66 IIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCL 130

  Fly   326 AVGMRPECV----------------VPENQCAMKRREKKAQK-EKDKMTTSPSSQHGG------- 366
            ||||..:.|                |.:::...::|:.:.|. |.:.:|.:......|
Zfish   131 AVGMSRDAVKFGRMSKKQRDSLYAEVQKHRLQQQQRDHQQQPGEAEPLTPTYGLSTNGLTELHDD 195

  Fly   367 -----NGSLASGGGQDF-VKKEILDLMTC-------------EP-----PQHATIPLL------- 400
                 ||....|...|. |....||:...             ||     |.....|..
Zfish   196 LSGYMNGHTPDGTKPDSGVSSFYLDIQPSPDQSGLDINGIKPEPICDFTPGSGFFPYCSFTNGET 260

  Fly   401 -PDEILAKCQ--ARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRH 462
             |...:|:.:  |:|| |.::.:.....:....|..::...:|::....|:|  .|....:....
Zfish   261 SPTVSMAELEHLAQNI-SKSHMETCQYLREELQQMTWQAFLQEEVENYQSKP--REVMWQLCAIK 322

  Fly   463 ITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSY 527
            |||    .:|.:|||||.:..|.::.|.|||.||||.|.||:.:||.|.:|..:::::| :.:..
Zfish   323 ITE----AIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFVRMCRAFDPQNNTVYF-DGKYA 382

  Fly   528 TRDSYKMAGMADNIEDLLHFCRQMFSMKVDNVEYALLTAIVIFS-DRPGLEKAQLVEAIQSYYID 591
            ..|.:|..|..|.|..:..|.:.:.||.:...|.||.:|.|:.| ||..|::...||.:|.....
Zfish   383 GPDVFKSLGCDDLISSVFEFGKNLCSMHLSEDEIALFSAFVLMSADRSWLQEKVKVEKLQQKIQL 447

  Fly   592 TLRIYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLK 636
            .|:..:...|..|.:    ..||:..::.||.|.:::.|...:.|
Zfish   448 ALQHVLQKNHREDGI----LTKLICKVSTLRALCSRHTEKLTAFK 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	41/105 (39%)
		NR_LBD_EcR	420..652	CDD:132736	60/217 (28%)
roraa	XP_017209577.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593378
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840