Protein Alignment EcR and pparaa

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_001154805.1
• Gene: pparaa / 563298
• ZFINID: ZDB-GENE-041210-169
• Length: 470
• Species: Danio rerio
• Alignment Length: 465
• Identity: 132/465 - (28%)
• Similarity: 204/465 - (43%)
• Gaps: 89/465 - (19%)

  Fly   219 DSVNSISSGRDDLSPSSSLNG--YSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTC 281
            |:....||..|.|:|:||.:.  :||:...|...|......      |.||.|||||:||....|
Zfish    58 DTAVDNSSILDVLTPASSPSSEVFSASTGQDENSSGSLTLE------CRVCADRASGFHYGVHAC 116

  Fly   282 EGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECV----VPENQCAM 342
            |||||||||::.....| .|..|.|::....|.|||.||.:|||||||....:    :|:::
Zfish   117 EGCKGFFRRTIRLKLEY-DKCERNCKIQKKNRNKCQYCRFRKCLAVGMSHNAIRFGRIPQSE--- 177

  Fly   343 KRREKKAQ----KEKDKMTTSPSSQHGGNGSLASGGGQDFVK---------KEILDLMTCEPP-- 392
            |:|.|..|    ||:.|      .|.....|||....:.::|         :..|...|..||
Zfish   178 KQRLKAEQDVSGKEEHK------CQQPDMRSLARQMHEAYLKHFHMNKAKARVFLTGKTSTPPFV 236

  Fly   393 -------QHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPD 450
                   |||...|: .::|....:.:|.:|                   |..|.:.|
Zfish   237 IHDMDTLQHAEKKLV-TQLLGNVASGDISTL-------------------QEREVEAR------- 274

  Fly   451 ENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHS 515
                    .|......::.||..:.|:||.:|.|..:...||:||||....|.:...:|...  :
Zfish   275 --------LFLFCQYASVATVTELTEYAKAVPGFADLDLNDQVTLLKYGVYEALFTLLASCM--N 329

  Fly   516 SDSIFFANNRSY-TRDSYK--MAGMADNIEDLLHFCRQMFSMKVDNVEYAL-LTAIVIFSDRPGL 576
            .|.:..|....: ||:..|  ....:|.:|....|..:..::::|:.:.|| :.||:...|||||
Zfish   330 KDGLLVAQGGGFITREFLKSLRKPFSDMMEPKFQFAMKFNALELDDSDLALFVAAIICCGDRPGL 394

  Fly   577 EKAQLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSL-KLKNR 640
            .....:|.||...|.:||:::.:.|..:|:   .:.|||..|.:||.|..::||:...: |.::.
Zfish   395 SNVPQIERIQESVIHSLRLHLTSNHPDNSL---LFPKLLQKLADLRQLVTEHAELVQEINKTEDA 456

  Fly   641 KLPKFLEEIW 650
            .|...|:||:
Zfish   457 SLHPLLQEIY 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	42/97 (43%)
		NR_LBD_EcR	420..652	CDD:132736	59/236 (25%)
pparaa	NP_001154805.1	NR_DBD_Ppar	98..181	CDD:143523	39/92 (42%)
		NR_LBD_PPAR	199..469	CDD:132730	74/308 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593368
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840