Protein Alignment EcR and nr1h5

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: XP_005166790.1
• Gene: nr1h5 / 557500
• ZFINID: ZDB-GENE-080403-3
• Length: 487
• Species: Danio rerio
• Alignment Length: 439
• Identity: 141/439 - (32%)
• Similarity: 212/439 - (48%)
• Gaps: 101/439 - (23%)

  Fly   249 KKSKKGPAPRV--QEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMY 311
            |:.:.|...||  |:|||:||||:||||||||||||||||||||||||.|||.||.|.:||||||
Zfish   113 KRPRMGHGARVKGQDELCVVCGDKASGYHYNALTCEGCKGFFRRSVTKKAVYHCKSGGSCEMDMY 177

  Fly   312 MRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQ 376
            ||||||:|||:||.||||..||::.|.||..||..|             .|:|.|:...::....
Zfish   178 MRRKCQDCRLRKCRAVGMLAECLLTEVQCQSKRLRK-------------GSKHRGHNGSSARAED 229

  Fly   377 DFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEED 441
            |:.:...:                  ...::...|.....:..|..::.:::           |.
Zfish   230 DYSESRSV------------------SSTSRINTRVSSGFSREQRCILNRIV-----------EA 265

  Fly   442 LRRIMSQPDEN------ESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACS 500
            .||.:.|.:.:      .|.|:      |.:|....:.:::|.:.:|.|..:...||.|||.:.|
Zfish   266 FRRYIIQDNTHCRVPLWSSLTN------THLTPPQTEKLLQFLRSVPGFDLLDSSDQNTLLSSAS 324

  Fly   501 SEVMMLRMARRYDHSSDSIFFA------NN---------RSYTRDSYKM---AGMADN-IEDLLH 546
            .|||.|.:|:::..:..|:..|      ||         .|....|:::   :|:.|. :..:::
Zfish   325 VEVMFLLLAQQFSENPTSVSTALYPANLNNSNPDWGKTLESKNGSSHRILTHSGLNDELLRSVVN 389

  Fly   547 FCRQMFSMKVDNVEYALLTAIVIF--SDRPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDSMSLV 609
            |...|.::.|...|||||||..:.  :|||.|.....||.:|.:.::     :|:|.|.......
Zfish   390 FLHSMVTIAVTEAEYALLTATAVLCSADRPTLRAVGCVENLQEFVLE-----LLSRVCCSCSQRT 449

  Fly   610 ------FYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDV 652
                  .:|:||..|||||||.:.:..:          ||   ::.||:
Zfish   450 GAQDPRRFARLLGRLTELRTLRHNHLTL----------LP---QQPWDL 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	66/89 (74%)
		NR_LBD_EcR	420..652	CDD:132736	64/264 (24%)
nr1h5	XP_005166790.1	NR_DBD_like	127..210	CDD:295381	63/82 (77%)
		NR_LBD	288..478	CDD:299703	54/204 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593334
Domainoid	1	1.000	131	1.000	Domainoid score	I5123
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940