Protein Alignment EcR and rarab

DIOPT Version :10

• Sequence 1: NP_724460.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: XP_005164086.1
• Gene: rarab / 555364
• ZFINID: ZDB-GENE-980526-72
• Length: 460
• Species: Danio rerio
• Alignment Length: 574
• Identity: 162/574 - (28%)
• Similarity: 243/574 - (42%)
• Gaps: 139/574 - (24%)

  Fly   166 GAGGGGIGGMGILHHANGTPNGLIGVVGGGGGV------GLGVGGGGVGGLGMQHTPRSDSVNSI 224
            |..|..:||..:.|:....|:.|       ||:      ||.|.|        ..||...:|.:.
Zfish    12 GGLGTPLGGFPMPHYPYFFPHML-------GGLSPPALPGLPVSG--------YSTPSPATVETQ 61

  Fly   225 SSGRDDLSPSSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFR 289
            |:..:::.||               .....|.|||.:. |.||.|::|||||....|||||||||
Zfish    62 STSSEEIVPS---------------PPSPPPPPRVYKP-CFVCQDKSSGYHYGVSACEGCKGFFR 110

  Fly   290 RSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKD 354
            ||:.|:.||.|...::|.::...|.:||.|||:|||.|||..|.|         |.::..:|:.|
Zfish   111 RSIQKNMVYTCHREKSCIINKVTRNRCQYCRLQKCLEVGMSKESV---------RNDRNKRKKDD 166

  Fly   355 KMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYN 419
            |                        |:|.|:.....|.....|     |.:.|......|||.
Zfish   167 K------------------------KQECLENYVLSPDTEKMI-----EQVRKAHQETFPSLC-- 200

  Fly   420 QLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAF 484
            ||.          .|...:..| .|:....|..:..:::|    |:..|.|    |||||.||.|
Zfish   201 QLG----------KYTTNNSAD-HRVALDVDLWDKFSELS----TKCIIKT----VEFAKQLPGF 246

  Fly   485 TKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADNIEDLLHFCR 549
            |.:...||||||||...::::||:..||....|::.|::..:..|.....||.....:.:..|..
Zfish   247 TTLTIADQITLLKAACLDILILRICTRYTPDQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAN 311

  Fly   550 QMFSMKVDNVEYALLTAI-VIFSDRPGLEKAQLVEAIQSYYIDTLRIYILNR-----HCGDSMSL 608
            |:..:::|:.|..||:|| ::..||..||::..|:.:|...::.|:||:.||     |
Zfish   312 QLLPLEMDDAETGLLSAICLLCGDRQDLEQSDKVDELQEPLLEALKIYVRNRRPHKPH------- 369

  Fly   609 VFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQITQEENERL 673
             .:.|:|..:|:||::..:.||...:||:   ::|         .::||.:|..|    |.:|.|
Zfish   370 -MFPKMLMKITDLRSISAKGAERVITLKM---EIP---------GSMPPLIQEML----ENSEGL 417

  Fly   674 ERAERMRASVGGAITAGIDCDSASTSAAAAAAQHQPQPQPQPQPSSLTQNDSQH 727
            |......|..||....|......|.|             |...|||...:.|.|
Zfish   418 EGGGSKGAGGGGGGGGGKGAPPGSCS-------------PSLSPSSAHSSPSAH 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_724460.1	NR_DBD_EcR	261..351	CDD:143535	40/89 (45%)
		NR_LBD_EcR	420..652	CDD:132736	66/237 (28%)
rarab	XP_005164086.1	NR_DBD_RAR	80..155	CDD:143522	40/75 (53%)
		NR_LBD_RAR	184..413	CDD:132735	76/278 (27%)