Protein Alignment EcR and Eip78C

DIOPT Version :10

• Sequence 1: NP_724460.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_524195.2
• Gene: Eip78C / 40345
• FlyBaseID: FBgn0004865
• Length: 862
• Species: Drosophila melanogaster
• Alignment Length: 772
• Identity: 179/772 - (23%)
• Similarity: 275/772 - (35%)
• Gaps: 253/772 - (32%)

  Fly     6 SNNGGFMRLPEE------SSSEVTSSSNGLVLPSGVNMSPSSLDSHDYCDQDLWLCGNESGSFGG 64
            ||.||.:.....      :|:..||||           ||||..:|...|..   |.:.|.| |.
  Fly   212 SNGGGALYTISSVHQFGPASNHNTSSS-----------SPSSSAAHSSPDSG---CSSASSS-GS 261

  Fly    65 SNGHGLSQQQQSVITLAMHGCSSTLPAQTTIIPINGNANGNGGSTNGQYVPGATNLGALANGMLN 129
            |...|.|.           ..||:....:||        .:|.|:|...|..|....::|:
  Fly   262 SRSCGSSS-----------ASSSSSAVSSTI--------SSGRSSNNSVVNPAATSSSVAH---- 303

  Fly   130 GGFNGMQQQIQNGHGLINSTTPSTPTTPLHLQQNLGGAGGGGIGGMGILHHANGTPNGLIGVVGG 194
              .|..|||            ...|||.|..||.               |...
  Fly   304 --LNKEQQQ------------QPLPTTQLQQQQQ---------------HQQQ------------ 327

  Fly   195 GGGVGLGVGGGGVGGLGMQHTPRSDSVNSISSGRDDLSPSSSLNGYSANESCDAKKSKKGPAPRV 259
                             :||..:..|..        |:.|||.||.|.|.:   ..|.|...|
  Fly   328 -----------------LQHPQQQQSFG--------LADSSSSNGSSNNNN---GVSSKSFVP-- 362

  Fly   260 QEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKC 324
                |.||||:||||||...:|||||||||||:.|...|.|.....|.:....|.:||.||.|||
  Fly   363 ----CKVCGDKASGYHYGVTSCEGCKGFFRRSIQKQIEYRCLRDGKCLVIRLNRNRCQYCRFKKC 423

  Fly   325 LAVGMRPECV----VP---------------------------------------ENQCAMKRRE 346
            |:.||..:.|    ||                                       :.|..:.:::
  Fly   424 LSAGMSRDSVRYGRVPKRSRELNGAAASSAAAGAPASLNVDDSTSSTLHPSHLQQQQQQHLLQQQ 488

  Fly   347 KKAQKEKD------------------------------KMTTSPSSQHG---------------- 365
            ::.|.:..                              .:.:|||...|
  Fly   489 QQQQHQPQLQQHHQLQQQPHVSGVRVKTPSTPQTPQMCSIASSPSELGGCNSANNNNNNNNNSSS 553

  Fly   366 GNGSLAS---------GGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQL 421
            ||.|..|         ||.|..|...::.:.......| .:.:..|.:..          |.|:|
  Fly   554 GNASGGSGVSVGVVVVGGHQQLVGGSMVGMAGMGTDAH-QVGMCHDGLAG----------TANEL 607

  Fly   422 AVIYKLIWYQDGY-------EQPSEEDLRRIMSQPDENESQT---DVSFRHI-------TEITIL 469
            .|...::.....:       |:.:.|.:||.::.|....:.|   .:.|:.|       ..:| .
  Fly   608 TVYDVIMCVSQAHRLNCSYTEELTRELMRRPVTVPQNGIASTVAESLEFQKIWLWQQFSARVT-P 671

  Fly   470 TVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSY-TRDSYK 533
            .||.||||||.:|.|....|:||:.|:|....||.:..:||..:.::.::   ::.:| ||...:
  Fly   672 GVQRIVEFAKRVPGFCDFTQDDQLILIKLGFFEVWLTHVARLINEATLTL---DDGAYLTRQQLE 733

  Fly   534 MAGMADNIEDLLHFCRQMFSMKVDNVEYALLTAIVIF-SDRPGLEKAQLVEAIQSYYIDTLRIYI 597
            :...:|.:..||:|...:.:..:.:.|..|.:|:|:. |||.||.:.:::...:....:.||:.|
  Fly   734 ILYDSDFVNALLNFANTLNAYGLSDTEIGLFSAMVLLASDRAGLSEPKVIGRARELVAEALRVQI 798

  Fly   598 LNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLK--NRKLPKFLEEIWDV 652
            |....|...:|.....|.:.:.|||:||.::......|::.  ..:||....||:|:
  Fly   799 LRSRAGSPQALQLMPALEAKIPELRSLGAKHFSHLDWLRMNWTKLRLPPLFAEIFDI 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_724460.1	NR_DBD_EcR	261..351	CDD:143535	41/132 (31%)
		NR_LBD_EcR	420..652	CDD:132736	63/252 (25%)
Eip78C	NP_524195.2	NR_DBD_DmE78_like	363..443	CDD:143539	40/79 (51%)
		NR_LBD_DmE78_like	659..854	CDD:132739	54/198 (27%)