Protein Alignment EcR and Eip75B

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Alignment Length: 861
• Identity: 201/861 - (23%)
• Similarity: 328/861 - (38%)
• Gaps: 274/861 - (31%)

  Fly    68 HGLSQQQQSVITLAMHGCSSTLPAQTTIIPINGNANGNGGSTNGQY--VPGATNLGALANGMLNG 130
            |...||.|..:..::...||:            :|.|:|||::...  .|       :.:...:.
  Fly   338 HQQHQQHQQHVIASVSSSSSS------------SAIGSGGSSSSHIFRTP-------VVSSSSSS 383

  Fly   131 GFNGMQQQIQNGHGLINST-TPSTPTTPLHLQQNLGGAGGGGIGGMGILHHANGTPNGLIGVVGG 194
            ..:..|||.|....|.||. .|..|..|..::                  ||:.:.:|
  Fly   384 NMHHQQQQQQQQSSLGNSVMRPPPPPPPPKVK------------------HASSSSSG------- 423

  Fly   195 GGGVGLGVGGGGVGGLGMQHTPRSDSVNSISSGRDDLSPSSSLNGYSANESCDAKKSKKGPAPRV 259
                                ...|.:.|:.||..:...||||:                   |.:
  Fly   424 --------------------NSSSSNTNNSSSSSNGEEPSSSI-------------------PDL 449

  Fly   260 QEE----LCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVY--CCKFGRACEMDMYMRRKCQE 318
            :.:    ||.||||:|||:||...:|||||||||||:.:...|  |.| .:.|.:....|.:||.
  Fly   450 EFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTK-NQQCSILRINRNRCQY 513

  Fly   319 CRLKKCLAVGMRPECV----VPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFV 379
            ||||||:||||..:.|    ||           |.:|.:.......|:|:.|.        |..:
  Fly   514 CRLKKCIAVGMSRDAVRFGRVP-----------KREKARILAAMQQSTQNRGQ--------QRAL 559

  Fly   380 KKEILD------------LMTCEPPQHATIPLLPDEILAKCQ-ARNIPSLTYNQLAVIYKLIWYQ 431
            ..|:.|            |.|||        ...:::.|..| ||:.||
  Fly   560 ATELDDQPRLLAAVLRAHLETCE--------FTKEKVSAMRQRARDCPS---------------- 600

  Fly   432 DGYEQPSEEDLRRIMSQP----DENESQTDVS--FRHITEITILTVQLIVEFAKGLPAFTKIPQE 490
              |..|:      :::.|    .|.:|:.:.|  |.|:       ::.:::||..:|.|..:.|:
  Fly   601 --YSMPT------LLACPLNPAPELQSEQEFSQRFAHV-------IRGVIDFAGMIPGFQLLTQD 650

  Fly   491 DQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADNIED-LLHFCRQMFSM 554
            |:.|||||...:.:.:|:...:|.|.:||...|.:...||:.:....|..:.| ..:|..:|.||
  Fly   651 DKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNGANARFLVDSTFNFAERMNSM 715

  Fly   555 KVDNVEYALLTAIVIFS-DRPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSIL 618
            .:.:.|..|..|||:.: |||||...:|:|.:.|.....|: ||:.::..|...  |.||||..:
  Fly   716 NLTDAEIGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQ-YIVAQNRPDQPE--FLAKLLETM 777

  Fly   619 TELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQITQEENER----------L 673
            .:||||...:.|.....:.::::|.:  :::|       |::.......::|:.          :
  Fly   778 PDLRTLSTLHTEKLVVFRTEHKELLR--QQMW-------SMEDGNNSDGQQNKSPSGSWADAMDV 833

  Fly   674 ERAERMRASVGGAITAGIDCDSASTSAAAAAAQHQPQPQPQPQPSSL------------------ 720
            |.|:....||....:|.:|..|.|:|.....:...|   ||.|||:|
  Fly   834 EAAKSPLGSVSSTESADLDYGSPSSSQPQGVSLPSP---PQQQPSALASSAPLLAATLSGGCPLR 895

  Fly   721 ------TQNDS-----------QHQTQPQLQPQLPPQLQGQLQPQLQPQL--------------- 753
                  :..||           .|.||..|  .:.|.::.|.|.|.|.|:
  Fly   896 NRANSGSSGDSGAAEMDIVGSHAHLTQNGL--TITPIVRHQQQQQQQQQIGILNNAHSRNLNGGH 958

  Fly   754 ----QTQLQPQIQPQ-----PQLLPVSAPVPASVTA---PGSLSAVSTSSEYMGGSAAIGPITPA 806
                |.|..||:...     .:...:.:|..:.:.:   .....|||:     |||::..    :
  Fly   959 AMCQQQQQHPQLHHHLTAGAARYRKLDSPTDSGIESGNEKNECKAVSS-----GGSSSCS----S 1014

  Fly   807 TTSSITAAVTASSTTS 822
            ..||:..|:..|...:
  Fly  1015 PRSSVDDALDCSDAAA 1030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	43/99 (43%)
		NR_LBD_EcR	420..652	CDD:132736	62/239 (26%)
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	44/99 (44%)
		NR_LBD_REV_ERB	609..796	CDD:132738	58/196 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I8190
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010