Protein Alignment EcR and nhr-138

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_501730.3
• Gene: nhr-138 / 3565904
• WormBaseID: WBGene00003728
• Length: 410
• Species: Caenorhabditis elegans
• Alignment Length: 454
• Identity: 104/454 - (22%)
• Similarity: 177/454 - (38%)
• Gaps: 95/454 - (20%)

  Fly   255 PAPRV---QEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKC 316
            |.|||   ....||||||..:..||..:.|.||||||||||.:...|.|.....||:....|.:|
 Worm     3 PHPRVLNDNNRRCLVCGDDKASRHYGTVACNGCKGFFRRSVWEKRTYFCIANEDCEVLQQFRNRC 67

  Fly   317 QECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDF--- 378
            :.||..||:.|||....|..|.:.   |..:.|:|.|..:....||....|...:|......
 Worm    68 RACRFNKCVMVGMDARAVQSEREI---RPNETAKKPKGSLKGKRSSLQTSNSVTSSQPSSSSTPD 129

  Fly   379 -----VKKEILDLM----TCEPPQHATIPLLPDEILAK----CQAR-NIPSLTYN--QLAVIYKL 427
                 :.|.:.::.    |...|:.       |:::|:    |..| ::.|...|  ::|...||
 Worm   130 VDHPPIVKHLFNIQRRVETTFCPEF-------DDLVARFGSMCNVRISLQSALENPEKVATRTKL 187

  Fly   428 IWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQ 492
            .|                     .|.|:    ...|.::.:...:..|.|...|.:|.::.:.:.
 Worm   188 EW---------------------GNTSR----LADIHDLKVTWCRTFVWFHDYLSSFEELERLNY 227

  Fly   493 ITLLKACSSEVMMLRMA---------RRYDHSSDSIFFANNRSYTRDSYKMAGMADNIED----- 543
            :.     ..::..||.|         ..|.::.|.:.|.|:..|..|..|.|.|.....|
 Worm   228 LD-----REQLFKLRFAPVSWNLYAWHSYQNNIDGVTFTNDAWYPLDKEKQAFMDKPCNDYYSKI 287

  Fly   544 ---LLH-FCRQMFSMKVDNVEYALLTAIVIFSDRP----GLEKAQLVEAIQSYYIDTLRIYILNR 600
               ::| ...:|..:.:...|::.:.||.:|  ||    ..:..:|::.....:...|..|:|:|
 Worm   288 ADTMIHGLVYRMKGINMTEEEFSCMLAITLF--RPDYRLSSDANKLLQLTGDVFTKALSEYVLSR 350

  Fly   601 HCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQ 664
            ...:..::...|.|:.:||.:::|..|..:....|.         :.::.|:..:|..|.|.|:
 Worm   351 ETSELKAMERMATLMIMLTSVQSLARQEDDNVTFLA---------IFDMADLVGLPYEVHSALR 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	36/89 (40%)
		NR_LBD_EcR	420..652	CDD:132736	44/253 (17%)
nhr-138	NP_501730.3	NR_DBD_HNF4A	15..90	CDD:143518	34/74 (46%)
		HOLI	205..374	CDD:214658	34/175 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165562
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840