Protein Alignment EcR and raraa

DIOPT Version :10

• Sequence 1: NP_724460.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: XP_005156109.1
• Gene: raraa / 30680
• ZFINID: ZDB-GENE-980526-284
• Length: 447
• Species: Danio rerio
• Alignment Length: 504
• Identity: 149/504 - (29%)
• Similarity: 227/504 - (45%)
• Gaps: 110/504 - (21%)

  Fly   231 LSPSS----SLNGYS------------ANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNAL 279
            |||.|    .|:|||            ::|..........|.||:.:. |.||.|::|||||...
Zfish    30 LSPPSLPTLPLSGYSTPSPATIETQSTSSEEIVPSPPSPPPPPRIYKP-CFVCQDKSSGYHYGVS 93

  Fly   280 TCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKR 344
            .|||||||||||:.|:.||.|...:.|.::...|.:||.|||:|||.|||..|.|  .|....|:
Zfish    94 ACEGCKGFFRRSIQKNMVYTCHREKNCIINKVTRNRCQYCRLQKCLEVGMSKESV--RNDRNKKK 156

  Fly   345 REKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQ 409
            :|:|..:..:..|.||.::                  :::|.                  :.|..
Zfish   157 KEEKKPECTENYTLSPDTE------------------QMIDR------------------VRKAH 185

  Fly   410 ARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLI 474
            ....|||.             |.|....|....||:....|..:..:::|    |:..|.|
Zfish   186 QETFPSLC-------------QLGKYTTSNSSERRVALDVDLWDKFSELS----TKCIIKT---- 229

  Fly   475 VEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMAD 539
            |||||.||.||.:...||||||||...::::||:..||....|::.|::..:..|.....||...
Zfish   230 VEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGP 294

  Fly   540 NIEDLLHFCRQMFSMKVDNVEYALLTAI-VIFSDRPGLEKAQLVEAIQSYYIDTLRIYILNR--- 600
            ..:.:..|..|:..:::|:.|..||:|| ::..||..||:|..|:.:|...::.|:||:.||
Zfish   295 LTDLVFAFANQLLPLEMDDAETGLLSAICLLCGDRQDLEQADKVDVLQEPLLEALKIYVRNRRPH 359

  Fly   601 --HCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHL 663
              |        .:.|:|..:|:||::..:.||...:||:   ::|         .::||.:|..|
Zfish   360 KPH--------MFPKMLMKITDLRSISAKGAERVITLKM---EIP---------GSMPPLIQEML 404

  Fly   664 QITQEENERLERAERMRASVGGAITAGIDCDSASTSAAAAAAQHQPQPQ 712
                |.:|.||.:...:.|...|.|.|    |.|.|.:..:||..|..|
Zfish   405 ----ENSEGLESSSGAQGSRASATTPG----SCSPSLSPNSAQSSPPTQ 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_724460.1	NR_DBD_EcR	261..351	CDD:143535	43/89 (48%)
		NR_LBD_EcR	420..652	CDD:132736	67/237 (28%)
raraa	XP_005156109.1	NR_DBD_RAR	72..156	CDD:143522	42/86 (49%)
		NR_LBD_RAR	177..406	CDD:132735	76/291 (26%)