Protein Alignment EcR and nhr-117

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_001294719.1
• Gene: nhr-117 / 24104436
• WormBaseID: WBGene00003707
• Length: 477
• Species: Caenorhabditis elegans
• Alignment Length: 530
• Identity: 98/530 - (18%)
• Similarity: 177/530 - (33%)
• Gaps: 197/530 - (37%)

  Fly   235 SSLNGYSANESCDAKKSKKGPAPRVQE-----ELCLVCGDRASGYHYNALTCEGCKGFFRR---S 291
            :|::..||:.|..:..|.   .|.|.:     |.|.:|.....|||:.|..|..|..||||   |
 Worm     3 NSIDFCSASSSTSSNYSS---PPAVLDIDQVLEKCQICYQPGHGYHFGAFICRACAAFFRRCHFS 64

  Fly   292 VTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKM 356
            :......|.....:|:.:...|..|::||..|||.:||....:               |.::|..
 Worm    65 LALDQRKCRLLSGSCQPNKNGRWFCKKCRFDKCLELGMTTTNI---------------QYDRDAF 114

  Fly   357 TTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQL 421
            .:|.|...  |.|:|         |.:.|        ..::|:               ..:.||.
 Worm   115 KSSASFLK--NKSVA---------KRVAD--------RVSVPM---------------QFSSNQR 145

  Fly   422 AVIYKLIWYQDGYEQPS----------EEDLRRIMSQ-----------------PDENE------ 453
            .|||.:   ::.::.|.          :|..:||:.|                 .|||:
 Worm   146 HVIYNV---KNVFQTPPTALGKAGRTLDETDQRILCQNTVESALGINPIMIFTYADENKQFPFID 207

  Fly   454 -SQ----------TDVSFRHITEITILTVQLIVEFAKGLPAF--TKIPQEDQITLLKA------- 498
             ||          |.:|.|.|.:::.|.     :..:||..|  |:.....||..|.|
 Worm   208 ISQLVDKALSSILTPISVRKIKKMSNLE-----QLTQGLDEFQWTQKESVSQIVRLSANDHLNDF 267

  Fly   499 ----CSSEVMM------------------------------------LRMARR------------ 511
                |::...:                                    :|..|:
 Worm   268 QTYMCAAAKWLSYSDRIRNLDDELKIQILQCIWFNWGRLERIATTAKMRNKRKCGKKQFVFSNNI 332

  Fly   512 ---YDHSSDSIFFANNRSYTRDSYKMAGMADNIEDLLHFCRQMFSMKVDNVEYALLTAIVIF--- 570
               ||..|..:.|.:|.::....|.........::::  | :|..::.||:|...:.:::.|
 Worm   333 LLDYDEMSSDLSFWSNYTFEEMKYFFIPTEMFYDEVI--C-EMEEVQPDNMETTFIISLMCFHLT 394

  Fly   571 SDRPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSL 635
            ..:.|.:..:.::.:|....|.|..|.|.:      ::..|:..|..|.:::..         .|
 Worm   395 GKQFGGQVQEEMDQLQDLLSDELHEYYLKK------NMTMYSLRLKQLMKIKEK---------FL 444

  Fly   636 KLKNRKLPKF 645
            ||:.::..|:
 Worm   445 KLRYKRCEKY 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	25/97 (26%)
		NR_LBD_EcR	420..652	CDD:132736	55/337 (16%)
nhr-117	NP_001294719.1	ZnF_C4	33..103	CDD:197701	23/69 (33%)
		Hormone_recep	248..453	CDD:278530	31/222 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165497
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840