Protein Alignment EcR and unc-55

DIOPT Version :10

• Sequence 1: NP_724460.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_001122482.2
• Gene: unc-55 / 192082
• WormBaseID: WBGene00006790
• Length: 370
• Species: Caenorhabditis elegans
• Alignment Length: 462
• Identity: 101/462 - (21%)
• Similarity: 175/462 - (37%)
• Gaps: 139/462 - (30%)

  Fly   228 RDDLSPSSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSV 292
            :|..|.::||    .|.|.||..             |:||||::||.||...:|||||.||:||:
 Worm     2 QDGSSGAASL----GNSSPDATD-------------CVVCGDKSSGKHYGQFSCEGCKSFFKRSI 49

  Fly   293 TKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMT 357
            .:|..|.|:..:.|.:|:..|.:||.|||.||:.:|||                |:.::..:..|
 Worm    50 RRSLSYTCRATKNCAIDVQHRNQCQYCRLTKCIRMGMR----------------KEGRRSNETQT 98

  Fly   358 TSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQ---HATIPLLPDEILAKCQARNIPSLTYN 419
            ...:.|.|               :..:.:.:..||.   .:..|.:              |:.:|
 Worm    99 AVSAVQRG---------------RLPVTMPSLFPPNMFLRSPFPFM--------------SVPFN 134

  Fly   420 QLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAF 484
            .|                    :....::|...||        |.|....|:...|.:|:  .:.
 Worm   135 PL--------------------MTAQFTKPSIKES--------IFEFAAQTIFATVNWAR--TSM 169

  Fly   485 TKIPQEDQITLLKACSSEVMMLRMAR-------------------RYDHSSDSIFFANNRSYTRD 530
            :.:.:.||:.||:...:.:.:..:|:                   ..::.|.|:     .|.:.|
 Worm   170 SNLVKGDQLILLRHSWTPIFIFALAQSNFALNLSTHLTAVTATAASTENGSSSL-----GSKSED 229

  Fly   531 SYKMAGMADNIEDLLHFCRQMFSMKVDN--------VEYALLTAIVIFS-DRPGLEKAQLVEAIQ 586
            ..|.....:.:.|...|  |.|..|:|.        ||.:.|.|:::|| |...||:...:|.|
 Worm   230 EEKSEEKPERVFDEPQF--QGFQAKIDKIRDFHLDVVESSSLRAVLLFSCDEEALEEKGKIEEI- 291

  Fly   587 SYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTELRTLGN-QNAEMCFSLKLKNRKLPKFLEEIW 650
               ::.|:..: :.:|..:.....|.::...|..|::..| ..:.:.||..|....|...|.
 Worm   292 ---VEKLKSAV-DEYCKMNKRSERYHQICECLQLLKSTRNLPISRLFFSRLLGTTPLETILS--- 349

  Fly   651 DVHAIPP 657
            |:...||
 Worm   350 DLLITPP 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_724460.1	NR_DBD_EcR	261..351	CDD:143535	35/89 (39%)
		NR_LBD_EcR	420..652	CDD:132736	47/260 (18%)
unc-55	NP_001122482.2	NR_DBD_COUP_TF	21..89	CDD:143516	34/83 (41%)
		NR_LBD_F2	148..325	CDD:132728	39/198 (20%)