Protein Alignment EcR and nhr-73

DIOPT Version :10

• Sequence 1: NP_724460.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_492921.2
• Gene: nhr-73 / 191722
• WormBaseID: WBGene00003663
• Length: 326
• Species: Caenorhabditis elegans
• Alignment Length: 325
• Identity: 70/325 - (21%)
• Similarity: 113/325 - (34%)
• Gaps: 82/325 - (25%)

  Fly   264 CLVC-GDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAV 327
            |.|| ....:..::...:|..|..|||||  ....|.|....:|.:...|:..|:.||...|:..
 Worm    15 CQVCHSTERTRLYFGITSCAACAAFFRRS--DGIRYMCTATNSCTISHDMKFFCRACRYTSCIRA 77

  Fly   328 GMRPECVVPENQCAMKRREKK--AQKEKDKMTTSPSSQHGGNGSLASGGGQDFVK---------- 380
            ||    |:..|..|..|:...  ..:|....:.....:..|...:.:....|.:|
 Worm    78 GM----VMSRNALATARKAPNNIIPREPTPRSVPSLEEVDGFSKILNISNGDLLKYYVKEVESIM 138

  Fly   381 --------------KEILDLMTCEPPQHATIPLLPDEILAKCQARNIP--SLTYNQ-LAVIYKLI 428
                          |.:.|||.....|..|       .|..|  .|.|  .:.||: :.|::|..
 Worm   139 AQQRYGEQKNALQVKSVNDLMIVTAYQEGT-------SLESC--FNCPGVDILYNEDVEVVHKYF 194

  Fly   429 -----WYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITI--LTVQL---IVEFA--KGL 481
                 |........|..|       |..||..::  |.|:.:.|:  ...||   |:|:|  |..
 Worm   195 KFSNTWIDSLLAPTSPLD-------PSCNERISE--FIHLLKSTLGSTLAQLNLNIIEYAAFKSF 250

  Fly   482 PAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMA--GMADNIEDL 544
            ..:..:..:..|: :|..:.|        .|:..:.::     |.|.|.:.||:  .||..|.|:
 Worm   251 CIWKLVYHKTSIS-MKIVAQE--------HYEGVTSAL-----RKYYRKNIKMSELEMATRIGDI 301

  Fly   545  544
             Worm   302  301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_724460.1	NR_DBD_EcR	261..351	CDD:143535	24/89 (27%)
		NR_LBD_EcR	420..652	CDD:132736	30/140 (21%)
nhr-73	NP_492921.2	ZnF_C4	15..79	CDD:197701	18/65 (28%)
		HOLI	168..311	CDD:214658	37/166 (22%)