Protein Alignment EcR and nhr-233

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_507191.2
• Gene: nhr-233 / 189569
• WormBaseID: WBGene00006471
• Length: 302
• Species: Caenorhabditis elegans
• Alignment Length: 365
• Identity: 68/365 - (18%)
• Similarity: 125/365 - (34%)
• Gaps: 106/365 - (29%)

  Fly   289 RRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEK 353
            |::|.|:....|....:|.....:...||.||.:|.:.|||..:
 Worm     5 RQAVRKTPFKPCIQQESCYQAAPLNFGCQLCRFQKSIEVGMNIQ--------------------- 48

  Fly   354 DKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTY 418
                                                        |||        |..:|..|.:
 Worm    49 --------------------------------------------PLL--------QKTSIQELLH 61

  Fly   419 NQLA-----VIYKLIWYQDGYEQPSEEDLRR---IMSQPDENESQTDVSFRHITEITILTVQLIV 475
            :..|     |...|..|.:......|:.||.   .:::...:|...| |:.:||.::      .|
 Worm    62 DISAHHMNRVFLLLNSYPENSNLKIEQMLREETSFVARQKYHEMNWD-SWYYITLVS------TV 119

  Fly   476 EFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMA-RRYDHSSDSIFFANNRSYTRDSYKMAGMAD 539
            .|.|..|.......:|:|.:::....:|.:...: |.|....:.|.|.:..|..........:.|
 Worm   120 YFMKQFPFVYFARLQDRIAIIRETFLKVALFSASFRAYALGKEVISFPDGSSIFPSKETERIVKD 184

  Fly   540 -NIEDLL--HFCRQMFSMKVDNVEYALLTAIVIFSDRPGLEK-----AQLVEAIQSYYIDTL-RI 595
             |:.:|:  ....:|..:::.|.|: ||..:::|.: |.:..     .:|:...|::|..:| :|
 Worm   185 LNMPELITGRLISKMRELQIANEEF-LLVLVILFCN-PAITNLSDTGRRLLSTYQNFYSSSLFKI 247

  Fly   596 YILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSL 635
            ..:|     :...|.:.:||| ||.|.....::....|.|
 Worm   248 CSMN-----NSGHVRFMELLS-LTNLAETAVKDVNQYFVL 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	13/61 (21%)
		NR_LBD_EcR	420..652	CDD:132736	49/234 (21%)
nhr-233	NP_507191.2	NR_DBD_like	<2..46	CDD:383039	12/40 (30%)
		HOLI	113..271	CDD:214658	37/171 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165601
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840