DRSC/TRiP Functional Genomics Resources

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Protein Alignment EcR and nhr-227

DIOPT Version :9

Sequence 1:NP_001163061.1 Gene:EcR / 35540 FlyBaseID:FBgn0000546 Length:878 Species:Drosophila melanogaster
Sequence 2:NP_001256013.2 Gene:nhr-227 / 188976 WormBaseID:WBGene00020851 Length:240 Species:Caenorhabditis elegans


Alignment Length:220 Identity:42/220 - (19%)
Similarity:69/220 - (31%) Gaps:88/220 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   263 LCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQE--------- 318
            :|.:|..:|.|.|:..:||..|..|||||.|..               :::|||..         
 Worm     6 VCRICELQADGTHFGVVTCRACAVFFRRSTTSK---------------WIKRKCMARSEDKLIII 55

  Fly   319 --------CRLKKCLAVGM--------RPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGN 367
                    .::.||.:..:        :||..:..|.|        ..:...|..||..|     
 Worm    56 VQAIWHVWSKVHKCASTALYRKSNPNAKPEQKIFRNMC--------MDRNLGKFDTSWMS----- 107

  Fly   368 GSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPD-------EILAKCQARNIPS-LTYNQLAVI 424
                     |:..:.::..|           |.|:       |.|.|....::.| ..:.||...
 Worm   108 ---------DYSTEHVIRFM-----------LTPNVYDFEIIEALGKLDPTDVESTFMFAQLCFE 152

  Fly   425 Y-------KLIWYQDGYEQPSEEDL 442
            |       .::...|.::|....||
 Worm   153 YAGKRFQGNILQITDRFQQVLSNDL 177

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EcRNP_001163061.1 NR_DBD_EcR 261..351 CDD:143535 23/112 (21%)
NR_LBD_EcR 420..652 CDD:132736 7/30 (23%)
nhr-227NP_001256013.2 ZnF_C4 7..>44 CDD:197701 15/51 (29%)
Hormone_recep 48..220 CDD:333840 25/163 (15%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C160165644
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

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