Protein Alignment EcR and nhr-226

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_503630.1
• Gene: nhr-226 / 188975
• WormBaseID: WBGene00020850
• Length: 387
• Species: Caenorhabditis elegans
• Alignment Length: 451
• Identity: 96/451 - (21%)
• Similarity: 158/451 - (35%)
• Gaps: 162/451 - (35%)

  Fly   263 LCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVY--CCK--FGRACEMDMYMRRKCQECRLKK 323
            ||.:||..|.|.|:..:||..|..|||||.....::  |.|  .|:.|        .|:.|||:|
 Worm     7 LCRICGKNAHGTHFGVITCRACGVFFRRSFKSKWIFKKCKKEDEGKIC--------TCKPCRLQK 63

  Fly   324 CLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTT---SPSSQHGGNGSLASGGGQDFVKKEILD 385
            |:.:||               ..|..|.::|.:..   :||..:             ||.:...
 Worm    64 CVEMGM---------------SSKNFQYDRDAILAKHLTPSISY-------------FVGRPEF- 99

  Fly   386 LMTCEPPQHATIPLLP-DEILAKCQ--ARN-IPSLTY-----NQLAVIYKLIWYQDGYEQPSEED 441
            |:.|:|...|...|:. |.::::..  .|| :.|:.:     .:||:..|::          :.|
 Worm   100 LLFCDPSHSAPKILINLDGLVSEASRLLRNGVESVVFAETQLKKLALGLKVM----------QAD 154

  Fly   442 LRRI-----MSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKA--- 498
            :|.:     :.:|:         |..|.|....||   :::......|.|:.|..|:.|:::
 Worm   155 MRSLKYFEKIGKPE---------FLDIIEYYFTTV---IKWISHFDEFRKLDQNIQMKLVQSIWH 207

  Fly   499 -------CSSEVMMLRMARRYDHSSDSIF-----FANNRSYTRDSYKM--AGMADNIEDLLHFCR 549
                   ||:.|       .|..|||...     ...|....|:..||  :.|:|  ....|..|
 Worm   208 ILMKFHKCSATV-------AYRKSSDEKTRQLQKVIRNVCLDREKMKMDFSWMSD--YPAHHVLR 263

  Fly   550 QMFSMKVDNVEYALLTAIVIFSDRPGLEKAQLVEAIQSYYIDTLRI---YILNRHCGDSMSLVFY 611
            .|||.|..:.|                    ::|::..  :|...:   |:..:.|.:.....|.
 Worm   264 CMFSHKSYDFE--------------------IIESLSK--VDPTDVELTYMFAQSCFEYAGKRFQ 306

  Fly   612 AKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQITQEENER 672
            ..:|.|...            |...|.|           |:|        |..||::..||
 Worm   307 GDILKITDH------------FQQVLSN-----------DLH--------HYYITEQRRER 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	28/91 (31%)
		NR_LBD_EcR	420..652	CDD:132736	46/256 (18%)
nhr-226	NP_503630.1	ZnF_C4	7..69	CDD:197701	25/69 (36%)
		Hormone_recep	157..361	CDD:278530	48/254 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165641
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840