Protein Alignment EcR and nhr-127

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_001370055.1
• Gene: nhr-127 / 188480
• WormBaseID: WBGene00003717
• Length: 355
• Species: Caenorhabditis elegans
• Alignment Length: 379
• Identity: 88/379 - (23%)
• Similarity: 146/379 - (38%)
• Gaps: 105/379 - (27%)

  Fly   264 CLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFG-RACEMDMYMRRKCQECRLKKCLAV 327
            |.||.::::|||:..|:|..|..||||||.....|.||.| :.|::....|..|:.||..||:..
 Worm    13 CEVCKNQSNGYHFEVLSCGACASFFRRSVVSKIKYQCKDGKKRCQIRYLDRHFCRYCRFSKCVKA 77

  Fly   328 GMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPP 392
            ||:.|               |.||.:| :.:||:.....|                     |.|.
 Worm    78 GMKAE---------------KIQKNRD-LDSSPTPTDQNN---------------------CIPS 105

  Fly   393 QHATIPLLPDEILAKCQARNIPSL-----TYNQLAVIYKLIWYQDGYE---QPSEEDLRRIMSQP 449
            .    .|..|.||.|    :|..|     .:|......||....:|.:   :..|.:..:|:.:.
 Worm   106 D----VLHDDGILIK----DIRGLFKQFNPHNASEGCSKLEKLTEGLQFIRRNQERECIKIIDEM 162

  Fly   450 DENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARR--- 511
            | :||..||.|:.|.  :..|..|...|      |.|:.:.:::.:|:.......:|....|
 Worm   163 D-SESLKDVQFKVIG--SCATWLLFSSF------FQKLEENEKVVILERLWHGWTVLEFLSRSLE 218

  Fly   512 -YDHS--SDSIFFANNRSYTR------DSYKMAG--MADNI-------------EDLLHFCRQMF 552
             :.:.  .:.|.|.::.:..|      :|.|.|.  .:::|             |..|||    .
 Worm   219 IFGNKVIDEKIVFISDNTAIRLITAFENSLKTASPKKSESIKKKLELSFSVIFDELALHF----I 279

  Fly   553 SMKVDNVEYALLTAIVIFS------DRPGLEKA-----QLVEAIQSYYIDTLRI 595
            :.|...:|.:.:...:::|      ....|||.     ||.:.:..||:..|::
 Worm   280 NWKPTEIEISYMQWQIVWSVAEQLLSGNSLEKGEHFTEQLSKDLHEYYVRELKL 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	30/87 (34%)
		NR_LBD_EcR	420..652	CDD:132736	42/217 (19%)
nhr-127	NP_001370055.1	ZnF_C4	12..82	CDD:197701	28/68 (41%)
		Hormone_recep	156..352	CDD:395054	38/191 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165506
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840