Protein Alignment EcR and nhr-214

DIOPT Version :10

• Sequence 1: NP_724460.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_510121.3
• Gene: nhr-214 / 188210
• WormBaseID: WBGene00011566
• Length: 334
• Species: Caenorhabditis elegans
• Alignment Length: 359
• Identity: 76/359 - (21%)
• Similarity: 116/359 - (32%)
• Gaps: 105/359 - (29%)

  Fly   264 CLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVY-CCKFGRACEMDMYMRR---KCQECRLKKC 324
            |:||......:.:....|..|..|||||:...:.: .||....|......|:   ||:.||..||
 Worm     7 CVVCESSTHLFKHGKYLCNSCDLFFRRSMEPWSFFGDCKHSWDCYKVSGTRKKFPKCRHCRFNKC 71

  Fly   325 LAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGG-NGSLASGGGQDFVKKEILDLMT 388
            :.||:          ..:.|..|.|...|.......:.:|.. |.|::|    ||.....||..
 Worm    72 VDVGL----------LTVSRYTKFADLIKYLFCLDANREHTFLNFSISS----DFDTNNFLDEK- 121

  Fly   389 CEPPQHATIPLLPDEILAKCQARNIPSLTY--------NQLAVIYKLIWYQDGYEQPSEEDLRRI 445
                        |...:.|..     .||:        |:|:.|.||          ...|..:.
 Worm   122 ------------PTRFIKKTH-----DLTFDCHGWAIMNKLSAIEKL----------RSLDFPKY 159

  Fly   446 MSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMAR 510
            :|..|                       :..|.||                 |...|.|:....|
 Worm   160 LSSKD-----------------------LKYFFKG-----------------AYFLEAMLTMAMR 184

  Fly   511 RYDHSSDSIFFANNRSYTRDSYKMAGMAD-NIEDLLHFCR---QMFSMKVDNVEYALLTAIVIFS 571
            .|....|.:.|.:.......|.:.||... |..:|:. |:   :...:|:...|..:::||. ||
 Worm   185 CYFCKEDLMHFPHGVDLFPVSVQEAGKIKLNFLNLIR-CQLVGKFIELKITREEIIMISAIA-FS 247

  Fly   572 DR--PGLE--KAQLVEAIQSYYIDTLRIYILNRH 601
            :.  |.|.  ...|:...|..|..:|..|.|.::
 Worm   248 NPAVPDLSFTGQNLLSCYQKLYTSSLLQYCLTKY 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_724460.1	NR_DBD_EcR	261..351	CDD:143535	25/90 (28%)
		NR_LBD_EcR	420..652	CDD:132736	37/190 (19%)
nhr-214	NP_510121.3	ZnF_C4	7..75	CDD:197701	20/67 (30%)
		HOLI	145..298	CDD:214658	37/189 (20%)