Protein Alignment EcR and nhr-130

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_503216.1
• Gene: nhr-130 / 187965
• WormBaseID: WBGene00003720
• Length: 440
• Species: Caenorhabditis elegans
• Alignment Length: 463
• Identity: 95/463 - (20%)
• Similarity: 165/463 - (35%)
• Gaps: 142/463 - (30%)

  Fly   264 CLVCGDRASGYHYNALTCEGCKGFFRRSVT-KSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAV 327
            |.||...|.|.|:.|::|..|..||||:.| ....|.||....|::....|.||::|||.:|..|
 Worm    37 CQVCALPAHGNHFGAISCRACAAFFRRACTGTKTTYKCKKQNNCDIWENGRYKCKKCRLDRCNEV 101

  Fly   328 GMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASG------------GGQDFV- 379
            ||.|               .:.|.::|.::.:....:..|.....|            |...|:
 Worm   102 GMDP---------------GRFQFDRDLISATEKYPNSKNFRRTFGMSRLPETIEHFLGRPHFII 151

  Fly   380 ----------KKEILDLMTCEPPQHATIPLLPDEILAKCQ------------ARNIPSLTYNQLA 422
                      :|..:||      ||         ::||..            |||    ...:||
 Worm   152 FLERHIYSHSEKNFVDL------QH---------LIAKASKLLELGSEKPLIARN----NLEKLA 197

  Fly   423 VIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFTK- 486
            :...|:     .:||:.....:::::..::|:.|      ..|...|||      ||.|..|..
 Worm   198 LGLNLV-----RDQPAGSHDVQLVTKLGKDEALT------FWETDFLTV------AKWLTYFDDF 245

  Fly   487 --IPQEDQITLLKA----------------------CSSEVMMLRMARRYDHSSDSIFFANNRSY 527
              :|...||.|||:                      |..:.:||......:..:..:.::....|
 Worm   246 QLLPHNQQILLLKSVWHVWNRLEKLALTATSRRQNVCEQKQLMLTYNSVCNPKTIELDYSWFTKY 310

  Fly   528 TRDSYKMAGMADNIED--LLHFCRQMFSMKVDNVEYALLTAIVIF---SDRPGLEKAQLVEAIQS 587
            .::  ::....|.:||  |......:.|::..::|...:...:.|   ..|.|.|..::.|..|.
 Worm   311 PKE--QLCFFFDEMEDYMLTSALDPLTSLEPTDIELTYMLCQLCFHYAGKRYGGEILEVTEKFQE 373

  Fly   588 YYIDTLRIYILN-----RHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLE 647
            ...|.|..|.:|     |:||.             |.::..:.|...:..:..:.|:.     |.
 Worm   374 NLADNLHDYYVNELNMPRYCGR-------------LNQMLKINNLIQQDIWEKRAKHE-----LA 420

  Fly   648 EIWDVHAI 655
            :::|:..|
 Worm   421 KVFDIFCI 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	29/87 (33%)
		NR_LBD_EcR	420..652	CDD:132736	48/266 (18%)
nhr-130	NP_503216.1	ZnF_C4	36..105	CDD:197701	28/67 (42%)
		Hormone_recep	210..416	CDD:278530	41/232 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165487
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840