Protein Alignment EcR and nhr-205

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_505588.1
• Gene: nhr-205 / 187567
• WormBaseID: WBGene00011002
• Length: 387
• Species: Caenorhabditis elegans
• Alignment Length: 463
• Identity: 104/463 - (22%)
• Similarity: 186/463 - (40%)
• Gaps: 126/463 - (27%)

  Fly   236 SLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCC 300
            |||.....:....|::||   |.     |.:|||...|:|:....|..|..||||:|.....:.|
 Worm     3 SLNFQFFEQGLSQKETKK---PN-----CAICGDVGDGHHFGLDACRACAAFFRRTVALGKKFEC 59

  Fly   301 KFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEK---DKMTTSPSS 362
            :...||:::..:|..|:.|||.|||.:||:..||.|       ||:|..::||   ..|..||:.
 Worm    60 RQQGACKINTIIRSICKSCRLNKCLNLGMKRSCVQP-------RRDKPQKEEKLILPSMNVSPAD 117

  Fly   363 QHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKL 427
                                 :::...|.|  ..:..:|  ||.|..|      .|.:|.....:
 Worm   118 ---------------------IEVSCIEVP--IAVEAMP--ILQKMLA------NYEKLKNSRNI 151

  Fly   428 IWYQDG---YEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKG-LPAFTKIP 488
            |..::|   :|:.:...|:                ||...||....:.|:.::... ...|..:|
 Worm   152 IHRREGDNIFEKRTPRSLK----------------FRETLEILSNEMSLVADWIGWCFNEFEFLP 200

  Fly   489 QEDQITLLKACSSEVMMLRMA---RRYDH-------SSDSIFFAN-NRSYTRDSYKMAG------ 536
            .:.:..|....|...::|..|   .::::       |.|.|...| ...:|.:..|:.|
 Worm   201 TDQKSILFSNFSVNFIVLERAFLTSKHNNLNQWVLQSGDYIQIDNLEEFFTDEQLKIDGTKLAKL 265

  Fly   537 MADNIEDLLHFCRQMFSMKVDNVEYALLTAIVIFSDRPGL-----EKAQLVEAIQS-------YY 589
            ...::|...:|.:.:.|.|::..:: |:..:::|.|. |:     |..::.:.::|       ||
 Worm   266 FKPSLEQNDNFHKLLKSEKIEMYDF-LVFVVLLFWDH-GIVGQTEECREISKKMKSNVTNEYIYY 328

  Fly   590 IDTLRIYIL---NRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWD 651
            :.    ||.   |..|..:|       |:||||.|:.:      :|   :|:.   ...|..::|
 Worm   329 LK----YIQKNENPVCQLTM-------LVSILTCLQRI------VC---RLRE---DMSLAHVFD 370

  Fly   652 VHAIPPSV 659
            .:.:||::
 Worm   371 GYTLPPNL 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	32/89 (36%)
		NR_LBD_EcR	420..652	CDD:132736	49/267 (18%)
nhr-205	NP_505588.1	ZnF_C4	22..91	CDD:197701	26/73 (36%)
		HOLI	178..355	CDD:214658	37/189 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165623
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840