Protein Alignment EcR and nhr-189

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_504065.2
• Gene: nhr-189 / 185913
• WormBaseID: WBGene00018545
• Length: 355
• Species: Caenorhabditis elegans
• Alignment Length: 453
• Identity: 107/453 - (23%)
• Similarity: 162/453 - (35%)
• Gaps: 138/453 - (30%)

  Fly   229 DDLSPSSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVT 293
            |:| ||.::...::|            ||:     |.:||..||.::|..|:|..||.||||.|.
 Worm     5 DEL-PSLAMELSTSN------------APK-----CTICGRDASCHNYGVLSCNACKMFFRRVVI 51

  Fly   294 KSAVYCCKFGRAC-EMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMT 357
            :...|.||....| |.......:|:.||.:|||.:||                 ...|.||.::
 Worm    52 EQLTYHCKKWNMCLENSGQPILQCKACRFEKCLQLGM-----------------TLGQLEKIQL- 98

  Fly   358 TSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLA 422
              |...|           .||....::                          :|:..|...:.
 Worm    99 --PDLIH-----------PDFKSDSLI--------------------------KNVMFLNSTKR- 123

  Fly   423 VIYKLIWYQDGYEQPSEEDL--RRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGLPAFT 485
              :||..:... |.|:.||:  |...|:......:..:|   :.|.:...:.:.||....|....
 Worm   124 --FKLCNFYTS-EDPTLEDMVQRTKRSRMKRKTGKQVIS---VEEWSFQAIYIAVEMFLSLDFMN 182

  Fly   486 KIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADNIEDLLHFCRQ 550
            .|..:|:|.||:..||:.|.|..|.|      |:....:|..|.|..::      ..|||   ..
 Worm   183 SIENDDKIVLLRNFSSKSMQLDSAMR------SLNAKVDRVITPDGNEV------YSDLL---LA 232

  Fly   551 MFS-----------------MKVDNVEYALLT-------AIVIFSDRPGLEKAQLVEAIQSYYID 591
            |||                 :||...|:|||.       ||...|:|    ..:|:...|..|..
 Worm   233 MFSIDFLNSIRSSLVVRVEELKVTEQEHALLNFLLFCNPAIHPLSER----TRRLLATRQKSYSS 293

  Fly   592 TLRIYIL--NRHCGDSMSLVFYAKLLS---ILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEI 649
            .|..|.|  .:..|.|.    :|.|||   ::.:.....|....:| .:.:...||.|.|.:|
 Worm   294 ALLQYCLLTYQQSGPSR----FADLLSLSHVINKTSEDANSLTTLC-QMYMPQVKLKKLLIDI 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	28/90 (31%)
		NR_LBD_EcR	420..652	CDD:132736	63/261 (24%)
nhr-189	NP_504065.2	ZnF_C4	21..89	CDD:197701	28/89 (31%)
		HOLI	164..324	CDD:214658	46/182 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165618
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840