Protein Alignment EcR and nhr-133

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_503602.1
• Gene: nhr-133 / 185729
• WormBaseID: WBGene00003723
• Length: 406
• Species: Caenorhabditis elegans
• Alignment Length: 441
• Identity: 98/441 - (22%)
• Similarity: 175/441 - (39%)
• Gaps: 101/441 - (22%)

  Fly   264 CLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVY---CCKFGRACEMDMYMRRKCQECRLKKCL 325
            |.:|...|.|.|:..|:|..|..||||:..::|.|   .|:.|.....|:|   :|:.||||||.
 Worm    11 CEICEQPAHGNHFGVLSCRACAAFFRRAALQNAKYQDRVCRKGNCIGNDLY---RCKICRLKKCC 72

  Fly   326 AVGMRPECVVPENQCAMKRREKKAQKEKDKMTTS--PS--SQHGGNGSLASG-GGQDFVKKEILD 385
            .|||               ...|.|.::|.:::|  |:  ::.....|||:. |..:|:
 Worm    73 EVGM---------------NSSKFQNDRDLISSSLRPTNYTKTSAPQSLANFLGRPEFI------ 116

  Fly   386 LMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYK---LIWYQDGYEQPSEEDLRRIMS 447
             :.|||.:.::...|.|          :.||.....|:..:   ..|..:.|.. |.|.|...|.
 Worm   117 -LCCEPDKASSTKRLVD----------VTSLVDKAWAIFQEDAAYSWSPNHYPN-SLEKLTFEME 169

  Fly   448 QPDENESQTDVSFRHITEITILTVQLIVE---------FAKGLPAFTKIPQEDQITLLKACSSEV 503
            :....||...:..  .|.|......|.:|         ||: ||.|:.:..:.:|.:||  :|.:
 Worm   170 EIKLKESSKKLEI--ATTIGRNEALLFLEQSFLGAAQWFAR-LPEFSMLDPQIKIDILK--TSWM 229

  Fly   504 MMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADNIEDLLHFCRQMFSMKVD-----NVEYAL 563
            :..|:    |..:.:..|...:....|.|.   ..||.      |....::|:|     |.....
 Worm   230 IWARL----DKLAATADFHRQKLLGNDVYM---WTDNT------CMNPGNVKIDIKWSSNYSVEQ 281

  Fly   564 LTAIVIFSDRPGLEK------AQLVEAIQSYYIDTLRI---YILNRHCGDSMSLVFYAKLLSILT 619
            |...::    |.:||      :.|||      :|...:   ::|.:.|.:|....:...:|....
 Worm   282 LRGFLV----PDIEKYWRHALSDLVE------LDPTNVELNFMLIQLCLNSAGQKYQGHVLEATE 336

  Fly   620 ELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQITQEEN 670
            ::..:.:.|....::.||   ||..:...:..:..|..::::.::..:|:|
 Worm   337 KILQIQSDNMHEYYTKKL---KLVNYSGRLARLMKINRAIEADVRDRKEKN 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	29/89 (33%)
		NR_LBD_EcR	420..652	CDD:132736	50/257 (19%)
nhr-133	NP_503602.1	NR_DBD_like	11..86	CDD:295381	30/92 (33%)
		Hormone_recep	176..383	CDD:278530	43/237 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165563
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840