Protein Alignment EcR and nhr-37

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_504683.1
• Gene: nhr-37 / 185727
• WormBaseID: WBGene00018412
• Length: 417
• Species: Caenorhabditis elegans
• Alignment Length: 476
• Identity: 105/476 - (22%)
• Similarity: 163/476 - (34%)
• Gaps: 151/476 - (31%)

  Fly   259 VQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRA-CEMDMYMRRKCQECRLK 322
            |.::.||||...::|.|:.||||..|..||||:......|.||.|.: |.:|...|..|::|||.
 Worm     2 VPDKSCLVCKKASNGMHFGALTCRACAAFFRRATVLKLQYKCKQGNSKCNIDGRGRYVCRQCRLT 66

  Fly   323 KCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLM 387
            ||.|:||               .|:|.|.:.|     |:  :...|.:...|..:|      ...
 Worm    67 KCKAIGM---------------NEEKVQLDYD-----PT--YSFRGLMEDSGSDEF------STP 103

  Fly   388 TCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDEN 452
            ...|.|....|    ..|::..:...|.:..|.|...           .|...|...::...::.
 Worm   104 NGSPAQSDYSP----TNLSRKNSVESPGIDPNFLFTF-----------SPKTPDKPNMVISFNDL 153

  Fly   453 ESQTDVSFRHIT-----EITILTVQLIVEFAKGLPAFTKIPQEDQITLLKA------------C- 499
            ..:.:.||.|.|     |:|.|| ..:.:|.|...|.::|...|::.|..|            |
 Worm   154 VKKIETSFSHKTKGDDCELTTLT-SALKKFRKNQKAQSQISFLDKVELKSAIDWLNDRIYMYSCW 217

  Fly   500 ---SSEVMMLRM-------------ARRYDH----------------------------SSDSIF 520
               |..:|.|.|             .|.::.                            .|..|.
 Worm   218 FSSSKSLMSLPMDQKMQLFRSSWNVVRTFERLEMSVKIFEEGVIRGGYILINDDLAMKLESTHID 282

  Fly   521 FANNRSYTRDSYKMAGMADNIEDLLH-----FCRQMFSMK--VDNVEYALLTAIVIFSDRPGLEK 578
            ||:....|...:...     .|..||     ..|.:..:|  .:.|.:.::..|       |||:
 Worm   283 FASITDLTNQYFNKL-----FEPFLHRYIDEVARPLLDLKPTTEEVVFCMVHLI-------GLEE 335

  Fly   579 AQL-------VEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLK 636
            ..|       .|.:::...|.:.:|..||     ..:..|:..|.||.:|          ..|:|
 Worm   336 GDLSHETREACEQMRAEIADQMHVYYTNR-----TDIKMYSHRLLILMKL----------VKSMK 385

  Fly   637 LKNRKLPKFLEEIW--DV-HA 654
            ..:|:..|..|..|  |: ||
 Worm   386 RISREKSKIKELFWLFDIFHA 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	33/90 (37%)
		NR_LBD_EcR	420..652	CDD:132736	56/309 (18%)
nhr-37	NP_504683.1	ZnF_C4	7..76	CDD:197701	31/83 (37%)
		Hormone_recep	189..393	CDD:278530	39/230 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165520
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840