Protein Alignment EcR and nhr-181

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_504139.1
• Gene: nhr-181 / 185483
• WormBaseID: WBGene00018189
• Length: 406
• Species: Caenorhabditis elegans
• Alignment Length: 389
• Identity: 97/389 - (24%)
• Similarity: 146/389 - (37%)
• Gaps: 108/389 - (27%)

  Fly   230 DLSPSSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSV-T 293
            |..||||        |.....|....:|....|.|.||||..:|..|.|..|.||..||||:| .
 Worm     7 DPRPSSS--------SSSVSTSSMSSSPSTSSESCAVCGDSVNGKRYGAPACLGCIVFFRRAVIN 63

  Fly   294 KSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTT 358
            ||...|.|.|. |.:....|..|:.|||:||..|||:||        |::||:....::...:.|
 Worm    64 KSQYKCWKKGN-CVITFASRCVCRCCRLRKCSHVGMKPE--------AIQRRDLLGPRKPKTILT 119

  Fly   359 SPSSQ---------HGGNGSLASGGGQ----DFVKKEILDLMTCEPPQHATIPLLPDEILAKCQA 410
            :..||         ...:.|..|..|:    .|....::.|...:..||....:...:.:...|.
 Worm   120 NDISQSIDVALNFLSSPHSSCESDTGEYSNTTFDIDSLVRLQHDQRSQHEAYGIHHIDTIGCFQM 184

  Fly   411 RNIPSLTYNQLA------VIYKLIWYQDGYEQPSE-----EDLRRIMSQPDENESQTDVSFRHIT 464
            :|  |..|::.|      .:.||     |.|..:|     |..|| :||.|:|...::..|
 Worm   185 KN--SGKYHKRARASDINFVLKL-----GLENANEWGNQFEPYRR-LSQTDKNSVLSEFGF---- 237

  Fly   465 EITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTR 529
                              ||..|.|.               .:.|:|.|   :..:...|.::..
 Worm   238 ------------------AFLLIDQG---------------YKTAQRAD---EGFWLLQNETFMH 266

  Fly   530 DSYKMA-----GMADNIE---DLLH-FCRQMF--------SMKVDNVEYALL-TAIVIFSDRPG 575
            .:|..|     .|.:|.|   :|.| |..::.        ::.:|..|.|:| |.:::....||
 Worm   267 PNYFFALSVEDAMKENAEQKAELHHSFVNELVKCVSDPFKNLHIDEFECAILKTVLLLTPSFPG 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	38/90 (42%)
		NR_LBD_EcR	420..652	CDD:132736	37/185 (20%)
nhr-181	NP_504139.1	NR_DBD_HNF4A	33..107	CDD:143518	36/82 (44%)
		HOLI	203..376	CDD:214658	36/174 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165528
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840