Protein Alignment EcR and nhr-180

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_503286.1
• Gene: nhr-180 / 185170
• WormBaseID: WBGene00017961
• Length: 399
• Species: Caenorhabditis elegans
• Alignment Length: 423
• Identity: 76/423 - (17%)
• Similarity: 153/423 - (36%)
• Gaps: 111/423 - (26%)

  Fly   257 PRV-----QEELCLVCG-DRASGYHYNALTCEGCKGFFRRSV-TKSAVYCCKFGRACEMDMYMRR 314
            |||     ..:.|.:|. ::..|.|:...:|..|..||||:| ::.:...|: |..|:     |:
 Worm     4 PRVSSTEISHKTCQICKVEKCHGNHFGVDSCRACAAFFRRTVHSRWSREKCQ-GGTCD-----RK 62

  Fly   315 K--CQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKM------TTSPSSQHGGNGSLA 371
            |  |:.|||::|...||..:               |.|..:|.:      ::.|||.
 Worm    63 KLLCKPCRLQQCFEGGMVTD---------------KFQYNRDLINPVYLKSSIPSSL-------- 104

  Fly   372 SGGGQDFVKKEILDLMTCEPPQHATIPL------------LPDEILAKCQARNIPSL-------- 416
                :..:.|....|::.:.|:..||.:            |...|...|....:..|
 Worm   105 ----ERLLGKPHFVLISDKNPKKTTIDVHRLLGEATKILNLGHAIPTYCGNNRLKKLSLAVHNNV 165

  Fly   417 TYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKGL 481
            |:.:|.||.:        ...||     |::..:....:......|..|...|.:.:.::..:.:
 Worm   166 TFEKLDVIKR--------ATKSE-----ILTNWEYYFKRVATCLNHFDEFKKLEIPMQLKLLQTI 217

  Fly   482 -------------PAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYK 533
                         ..:.|..:..:::.:...|..::.::     |...|..:|:|   :..:..|
 Worm   218 WHVWGRLEKITSSARYQKTVENSKLSEVVFQSGWIVDVK-----DVDIDCNWFSN---FPNEQVK 274

  Fly   534 MAGMADNIEDLLHFCRQMFSMKVDNVEYALLTAIVIF---SDRPGLEKAQLVEAIQSYYIDTLRI 595
            .. |.....||.:..:.:..:...:||...:.|.:.|   .:|...|..::.|..|:...:.|..
 Worm   275 NF-MLQTSTDLFNVIQYIHDLDPTDVELTYMLAQLCFQYAGNRHRGEIQEVCEQFQNVLSNDLHD 338

  Fly   596 YILNRHCGDSMSLVFYAKLLSILTELRTLGNQN 628
            |.||     .|.:..|::.::.:.::.....:|
 Worm   339 YYLN-----EMRMPRYSRRIAKMMQINNYVQRN 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	24/93 (26%)
		NR_LBD_EcR	420..652	CDD:132736	34/225 (15%)
nhr-180	NP_503286.1	ZnF_C4	15..82	CDD:197701	23/72 (32%)
		Hormone_recep	167..373	CDD:278530	34/227 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165645
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840