Protein Alignment EcR and nhr-179

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_001256000.1
• Gene: nhr-179 / 184562
• WormBaseID: WBGene00017512
• Length: 440
• Species: Caenorhabditis elegans
• Alignment Length: 506
• Identity: 101/506 - (19%)
• Similarity: 163/506 - (32%)
• Gaps: 171/506 - (33%)

  Fly   232 SPSSSLNGYSANESCDAKKSKKGPAPRVQE-------ELCLVCGDRASGYHYNALTCEGCKGFFR 289
            |||||              |:....|.:.|       |.|.||.....|:|:.|.||..|..|||
 Worm     6 SPSSS--------------SQNNSLPSLVELGISLIHEKCRVCDQPGHGFHFGAFTCRACSAFFR 56

  Fly   290 RS----VTKSAVYCCKF--GRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKK 348
            |:    ||:..   |:.  || |......|..|::|||.||...||               ..:.
 Worm    57 RAHFSLVTERK---CRLSNGR-CVPTKGGRWFCKKCRLAKCSEAGM---------------NSRN 102

  Fly   349 AQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILA------- 406
            .|.::|...||..|....|.::.:       |..|       |.:.|.|....:.:|.
 Worm   103 IQYDRDANKTSLLSSTNVNRNMKN-------KNAI-------PNKFALIYQTVESLLGISNLIIL 153

  Fly   407 ---KCQARNIPSLTYNQLA------VIYKLIWYQDGYEQPSEE---DLRRIMSQPDENESQTDVS 459
               :.:....|.:..:.|.      ::..::..:||.....|:   .|:.|.|...||
 Worm   154 LENRSEPNACPVVDISLLVDKATNYILNPVLIRKDGDMSNLEQLSLGLQDIQSSQKEN------- 211

  Fly   460 FRHITEITILTV--------QLIVEFAKGLPAFTKIPQED---QITLLK---------------- 497
               :.|...:|:        :.:...||.|....||...|   :|.:|:
 Worm   212 ---VLEKKFITIADHMKQFEKAMCATAKWLACSKKIQSFDDDVKIKILRTVWFNWGRLEHMTATA 273

  Fly   498 ------ACSSEVMM---------------LRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADNI 541
                  :|..|.:|               |....:|.......||:.|..|..::..
 Worm   274 KMRIRGSCGKEQLMFSSDTKLNFGNVHIDLSCFSKYSFEQMRYFFSPNEVYYDEAIS-------- 330

  Fly   542 EDLLHFCRQMFSMKVDNVEYALLTAIVIFSDRPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDS- 605
                    :|..|:..::|...|...:.| ...|......:|....:..|.|...:.:.:|.::
 Worm   331 --------KMVEMQPSDIELTYLICAICF-HITGKHFGGDIEEEMGHLQDVLASDLHDYYCKNNF 386

  Fly   606 -MSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAI 655
             |.|:...:||.|....             :||:|.:|.|:  ||..|..:
 Worm   387 PMYLLRLKQLLKIKDTF-------------VKLRNIRLEKY--EIGGVFKV 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	30/102 (29%)
		NR_LBD_EcR	420..652	CDD:132736	50/290 (17%)
nhr-179	NP_001256000.1	ZnF_C4	30..99	CDD:197701	28/87 (32%)
		HOLI	227..399	CDD:214658	31/188 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165499
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840