Protein Alignment EcR and nhr-177

DIOPT Version :9

• Sequence 1: NP_001163061.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_503455.1
• Gene: nhr-177 / 184557
• WormBaseID: WBGene00017503
• Length: 421
• Species: Caenorhabditis elegans
• Alignment Length: 456
• Identity: 90/456 - (19%)
• Similarity: 173/456 - (37%)
• Gaps: 103/456 - (22%)

  Fly   230 DLSPSSSLNGYSANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRR-SVT 293
            ::.|..|.:.:.:|.|.   .|.:.|.||..   |.:|.::..|||:...:|..|..|||| ...
 Worm     6 NICPRPSTSNHFSNISL---SSSEPPPPRKD---CRICFEKGHGYHFGVFSCRACAAFFRRCHFL 64

  Fly   294 KSAVYCCKFGRA-CEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMT 357
            |.....|:..:. |..:...:..|:.|||::|..:||.|..:..:.. |.|...||.:...:.:|
 Worm    65 KENRRRCRLSKGKCGPNKNGKWFCKTCRLERCFRLGMTPSNIQYDRD-AYKSSVKKIKDSAENIT 128

  Fly   358 TSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLA 422
                                            ||.:.||     ..||....::.:|.:..:||.
 Worm   129 --------------------------------EPKRDAT-----SLILINKTSQVLPYVDLSQLV 156

  Fly   423 -----VIYKLIWYQDGYEQPSEEDLRR--IMSQPDENESQTDVSFRHITEITILTVQLIVEFAKG 480
                 ::...|:.:...:..:.|.|..  |..|..:.::..:|....::::|....:.:...||.
 Worm   157 NKATRMLLNPIFTKKTKKMSNLEQLTHGLIELQWSQKDNLAEVVHLSVSDVTQDMERSMFGAAKW 221

  Fly   481 LPAFTKIPQ-ED--QITLLKAC---------SSEVMMLRMARRYD--HSSDSIFFANN---RSYT 528
            :....:|.. :|  :|.:|:|.         .:....||:.::.:  |...|..||.|   .|:.
 Worm   222 MMCSERIRNYQDSLKIRILQAIWYTWGRLERIATTAKLRLEKKCEEKHFVFSPMFALNLDEMSFD 286

  Fly   529 RDSYKMAGMADNIEDLLHF-----------CRQMFSMKVDNVEYALLTAIVIF---SDRPGLEKA 579
            ...:...    ..|::.:|           ..:|..:|.::||...:...:.|   ..|.|.|..
 Worm   287 ASCWTTL----PFEEMQYFYVPRELFYEDAVLEMMEVKPNDVETTFIICSICFHLTGKRFGGEIQ 347

  Fly   580 QLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPK 644
            :.::.:|....:.|..|.|...  :||    |.:.|..|..::    :|     .|||::.::.|
 Worm   348 EKMDHLQDVLSNDLHEYYLKNK--NSM----YLRRLKQLMRIK----EN-----FLKLRSARMDK 397

  Fly   645 F 645
            :
 Worm   398 Y 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_001163061.1	NR_DBD_EcR	261..351	CDD:143535	26/91 (29%)
		NR_LBD_EcR	420..652	CDD:132736	48/264 (18%)
nhr-177	NP_503455.1	ZnF_C4	34..104	CDD:197701	21/69 (30%)
		Hormone_recep	201..404	CDD:365875	40/217 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165498
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840